Evidence map›Paper›PMID 32060369›Full record

ArticleScientific reports2020

Aluminum and aluminum oxide nanomaterials uptake after oral exposure - a comparative study.

Benjamin C Krause, Fabian L Kriegel, Daniel Rosenkranz, Nadine Dreiack, Jutta Tentschert, Harald Jungnickel, Pegah Jalili, Valerie Fessard, Peter Laux, Andreas Luch

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
8.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The MAK collection for occupational health and safety · 2025
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  8. Article
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  10. Review
  11. Neuroprotective effect of sesamol against aluminum nanoparticle-induced toxicity in rats.Environmental science and pollution research international · 2021
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Benjamin C Krause *German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Straße 8-10, 10589, Berlin, Germany. Benjamin-christoph.krause@bfr.bund.de.
Fabian L Kriegel *German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Straße 8-10, 10589, Berlin, Germany.
Daniel Rosenkranz *German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Straße 8-10, 10589, Berlin, Germany.
Nadine DreiackGerman Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Straße 8-10, 10589, Berlin, Germany.
Jutta TentschertGerman Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Straße 8-10, 10589, Berlin, Germany.
Harald JungnickelGerman Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Straße 8-10, 10589, Berlin, Germany.
Pegah JaliliANSES, French Agency for Food, Environmental and Occupational Health and Safety, Fougères Laboratory, 10B rue Claude Bourgelat, 35306, Fougères Cedex, France.
Valerie FessardANSES, French Agency for Food, Environmental and Occupational Health and Safety, Fougères Laboratory, 10B rue Claude Bourgelat, 35306, Fougères Cedex, France.
Peter LauxGerman Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Straße 8-10, 10589, Berlin, Germany.
Andreas LuchGerman Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Straße 8-10, 10589, Berlin, Germany.
Federal Institute for Risk Assessment · DEAgence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The knowledge about a potential in vivo uptake and subsequent toxicological effects of aluminum (Al), especially in the nanoparticulate form, is still limited. This paper focuses on a three day oral gavage study with three different Al species in Sprague Dawley rats. The Al amount was investigated in major organs in order to determine the oral bioavailability and distribution. Al-containing nanoparticles (NMs composed of Al

Indexed as

Biological AvailabilityAdministration, OralAluminumAluminum ChlorideAluminum OxideAnimalsHumansIntestinesLiverNanostructuresRatsRats, Sprague-DawleySpleenTissue DistributionAluminumAluminum ChlorideAluminum Oxide

Identifiers

PMID32060369
PMCPMC7021764
OpenAlexW3006426830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.