Evidence map›Paper›PMID 32060194›Full record

SynthesisCanadian family physician Medecin de famille canadien2020

Intermittent fasting and weight loss: Systematic review.

Stephanie Welton, Robert Minty, Teresa O'Driscoll, Hannah Willms, Denise Poirier, Sharen Madden, Len Kelly

2 registry-linked trialsAbstract readSystematic Review
PubMed Full text at PMC
In one paragraph

Synthesis in Canadian family physician Medecin de famille canadien, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 105 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04502329 nacompletednot on this map

The Effect of Intermittent Fasting Diet on Metabolic Syndrome Biomarkers and Weight Management in Individuals With Metabolic Syndrome

TypeinterventionalSponsorIstanbul Medipol University HospitalRan2019 to 2020Enrolled65ConditionsMetabolic SyndromeArmsDiet
NCT06515639 nacompletednot on this mapstarted 2024, after this paper: background citation

Classic vs. High-Fat Intermittent Fasting: Impacts on Body Composition, Eating Behavior, and Diet Satisfaction

TypeinterventionalSponsorIstanbul Bilgi UniversityRan2024 to 2024Enrolled44ConditionsObesityArmsDiet therapy for Classic IF diet group, Diet therapy for low carb-High fat IF diet group
3 · Its place in the literature

Who cites it

105 citing papers in PubMed, 13 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Obesity in South and Southeast Asia-A new consensus on care and management.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023
    Guideline
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Intermittent fasting for the prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2021
    Pooled it
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Trial
  20. Trial

45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephanie WeltonResearcher for the Anishinaabe Bimaadiziwin Research Program in Sioux Lookout, Ont.
Robert MintyFamily physician practising at the Sioux Lookout Meno Ya Win Health Centre and Assistant Professor in the Division of Clinical Sciences at the Northern Ontario School of Medicine.
Teresa O'DriscollAssistant Professor in the Division of Clinical Sciences at the Northern Ontario School of Medicine in Sioux Lookout.
Hannah WillmsResearch assistant in the Anishinaabe Bimaadiziwin Research Program.
Denise PoirierPrimary care nurse at the Hugh Allan Clinic in Sioux Lookout.
Sharen MaddenAssociate Professor in the Division of Clinical Sciences at the Northern Ontario School of Medicine in Sioux Lookout.
Len KellyResearch consultant for the Sioux Lookout Meno Ya Win Health Centre. lkelly@mcmaster.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the evidence for intermittent fasting (IF), an alternative to calorie-restricted diets, in treating obesity, an important health concern in Canada with few effective office-based treatment strategies. DATA SOURCES: A MEDLINE and EMBASE search from January 1, 2000, to July 1, 2019, yielded 1200 results using the key words STUDY SELECTION: Forty-one articles describing 27 trials addressed weight loss in overweight and obese patients: 18 small randomized controlled trials (level I evidence) and 9 trials comparing weight after IF to baseline weight with no control group (level II evidence). Studies were often of short duration (2 to 26 weeks) with low enrolment (10 to 244 participants); 2 were of 1-year duration. Protocols varied, with only 5 studies including patients with type 2 diabetes. SYNTHESIS: All 27 IF trials found weight loss of 0.8% to 13.0% of baseline weight with no serious adverse events. Twelve studies comparing IF to calorie restriction found equivalent results. The 5 studies that included patients with type 2 diabetes documented improved glycemic control.

conclusionIntermittent fasting shows promise for the treatment of obesity. To date, the studies have been small and of short duration. Longer-term research is needed to understand the sustainable role IF can play in weight loss.

Indexed as

FastingWeight LossBody Mass IndexFemaleHumansMaleObesityPrimary Health Care

Identifiers

PMID32060194
PMCPMC7021351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.