Evidence map›Paper›PMID 32060140›Full record

ArticlePediatrics2020

Hepatitis C Testing Among Perinatally Exposed Infants.

Susan M Lopata, Elizabeth McNeer, Judith A Dudley, Carolyn Wester, William O Cooper, James G Carlucci, Claudia M Espinosa, William Dupont, Stephen W Patrick

Abstract read
In one paragraph

Article in Pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Article
  3. Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Pediatric Hepatitis C Screening by Maternal Hepatitis C Infection Status During Pregnancy.Journal of the Pediatric Infectious Diseases Society · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Pregnancy as an Opportunity for Hepatitis C Virus Elimination and Eradication.The American journal of tropical medicine and hygiene · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. CDC Recommendations for Hepatitis C Testing Among Perinatally Exposed Infants and Children - United States, 2023.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2023
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Susan M LopataDepartments of Pediatrics, susan.m.lopata@vumc.org.
Elizabeth McNeerVanderbilt Center for Child Health Policy, Vanderbilt University Medical Center, Nashville, Tennessee.
Judith A DudleyHealth Policy, and.
Carolyn WesterTennessee Department of Health, Nashville, Tennessee; and.
William O CooperDepartments of Pediatrics.
James G CarlucciDepartments of Pediatrics.
Claudia M EspinosaDepartment of Pediatrics, School of Medicine, University of Louisville, Louisville, Kentucky.
William DupontBiostatistics, and.
Stephen W PatrickDepartments of Pediatrics.

Funding

Improving Access to Treatment for Women with Opioid Use DisorderR01DA045729 · NIDA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PATRICK, STEPHEN W · 2018 to 2021
$1.5M
Neonatal Abstinence Syndrome: Risk of Drug Withdrawal in Opioid-Exposed InfantsK23DA038720 · NIDA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PATRICK, STEPHEN W · 2015 to 2019
$844k
NIDA NIH HHS K23 DA038720NIDA NIH HHS R01 DA045729
6 · The paper itself

Abstract

backgroundHepatitis C virus (HCV) prevalence doubled among pregnant women from 2009 to 2014, reaching 3.4 per 1000 births nationwide. Infants exposed to HCV may acquire HCV by vertical transmission. National guidelines recommend that infants exposed to HCV be tested; however, it is unclear if these recommendations are being followed. Our objectives were to determine if infants exposed to HCV were tested and to determine hospital- and patient-level factors associated with differences in testing.

methodsIn this retrospective cohort study of infants exposed to HCV who were enrolled in the Tennessee Medicaid program, we used vital statistics-linked administrative data for infants born between January 1, 2005, and December 31, 2014. Infants were followed until 2 years old. Multilevel logistic regression was used to assess the association of HCV testing and hospital- and patient-level characteristics.

resultsOnly 23% of 4072 infants exposed to HCV were tested. Infants whose mothers were white versus African American (96.6% vs 3.1%;

conclusionsTesting occurred in <1 in 4 infants exposed to HCV and less frequently among African American infants. Public health systems need to be bolstered to ensure that infants exposed to HCV are tested for seroconversion.

Indexed as

Infectious Disease Transmission, VerticalNeonatal ScreeningAdultBlack or African AmericanChild, PreschoolCohort StudiesFemaleHepatitis CHIV InfectionsHumansInfantInfant, NewbornMaleMaternal-Fetal ExchangeMedicaidOffice Visits

Identifiers

PMID32060140
PMCPMC7049945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.