Evidence map›Paper›PMID 32060138›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

GCNT1-Mediated

Eric Perkey, Dave Maurice De Sousa, Léolène Carrington, Jooho Chung, Alexander Dils, David Granadier, Ute Koch, Freddy Radtke, Burkhard Ludewig, Bruce R Blazar and 5 more

Open access · greenAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 34 citations in OpenAlex.

  1. Post-Translational Regulation of CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Plasma Proteomic Signature Predicts Myeloid Neoplasm Risk.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  11. Article
  12. Multi Omics Applications in Biological Systems.Current issues in molecular biology · 2024
    Review
  13. Runx3 Regulates CD8International journal of molecular sciences · 2024
    Article
  14. Journal of proteome research · 2024
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 3 countries.

Eric PerkeyGraduate Program in Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0003-3275-3181
Dave Maurice De SousaCentre de Recherche de l'Hôpital Maisonneuve-Rosemont, Montreal, Quebec H1T 2M4, Canada.
Léolène CarringtonDivision of Hematology-Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104.ORCID 0000-0002-7352-3270
Jooho ChungLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109.
Alexander DilsLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0002-9052-4726
David GranadierLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109.
Ute KochÉcole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.ORCID 0000-0001-7914-7061
Freddy RadtkeÉcole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.ORCID 0000-0003-4315-4045
Burkhard LudewigInstitute of Immunobiology, Kantonsspital St. Gallen, 9007 St. Gallen, Switzerland.ORCID 0000-0002-7685-573X
Bruce R BlazarDivision of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0002-9608-9841
Christian W SiebelGenentech, South San Francisco, CA 94080.
Todd V BrennanCedars-Sinai Medical Center, Los Angeles, CA 90048.ORCID 0000-0001-5940-5262
Jeffrey NolzOregon Health and Sciences University, Portland, OR 97239; and.ORCID 0000-0003-4701-7419
Nathalie LabrecqueCentre de Recherche de l'Hôpital Maisonneuve-Rosemont, Montreal, Quebec H1T 2M4, Canada; nathalie.labrecque@umontreal.ca imaillar@pennmedicine.upenn.edu.ORCID 0000-0001-7563-1542
Ivan MaillardDivision of Hematology-Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104; nathalie.labrecque@umontreal.ca imaillar@pennmedicine.upenn.edu.ORCID 0000-0003-1312-6748
University of Michigan · USÉcole Polytechnique Fédérale de Lausanne · CHHôpital Maisonneuve-Rosemont · CAUniversity of Pennsylvania · USCedars-Sinai Medical Center · USKantonsspital St. Gallen · CHOregon Health & Science University · USUniversity of Minnesota · US

Funding

Trial Design and Biostatistical Support CoreP01CA065493 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI John E. Wagner · 1995 to 2026
$48.2M
MICHIGAN MEDICAL SCIENTIST TRAINING PROGRAMT32GM007863 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLLINS, KATHLEEN L. · 1985 to 2024
$38.3M
Enhancing Treg Therapeutic Efficacy in GVHDR01HL118979 · NHLBI · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, HIPPEN, KELI L · 2014 to 2025
$6.7M
Notch Signaling in AlloimmunityR01AI091627 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI PEAR, WARREN S · 2011 to 2025
$6.0M
T-CELL TARGETING FOR GVHDR01HL056067 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BLAZAR, BRUCE R · 1995 to 2022
$5.4M
In Vivo Prevention of Murine GVHDR37AI034495 · NIAID · UNIVERSITY OF MINNESOTA · PI Bruce R Blazar · 2017 to 2026
$5.4M
The role of secondary lymphoid organ fibroblastic cells in alloimmunityF30AI136315 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PERKEY, ERIC THOMAS · 2018 to 2021
$166k
CIHR PJT-14903CIHR PJT-152988NCI NIH HHS P01 CA065493NHLBI NIH HHS R01 HL056067NHLBI NIH HHS R01 HL118979NIAID NIH HHS F30 AI136315NIAID NIH HHS R01 AI091627NIAID NIH HHS R37 AI034495NIGMS NIH HHS T32 GM007863
6 · The paper itself

Abstract

Notch signaling is emerging as a critical regulator of T cell activation and function. However, there is no reliable cell surface indicator of Notch signaling across activated T cell subsets. In this study, we show that Notch signals induce upregulated expression of the

Indexed as

AnimalsBiomarkersBone Marrow TransplantationCD8-Positive T-LymphocytesDisease Models, AnimalFeasibility StudiesFemaleFlow CytometryGlycosylationGraft vs Host DiseaseHumansLeukosialinLigandsLymphocyte ActivationMaleMicebeta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-acetylglucosaminyl transferaseBiomarkersLeukosialinLigandsN-AcetylglucosaminyltransferasesReceptors, NotchSialomucinsSpn protein, mouse

Identifiers

PMID32060138
PMCPMC7306398
OpenAlexW3006464034

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.