Evidence map›Paper›PMID 32060044›Full record

ArticleClinical medicine & research2020

Inpatient Mortality and 30-Day Readmission Rates Associated with Troponin Testing in Patients without Acute Myocardial Infarction.

R Jay Widmer, Gibbs Wilson, Travis Haneke, Mary Lee, Jerry Fan, Arthur Davis, Ethan Fry, Kevin Kurian, Jonathan Urbanczyk, Jordan Potter and 4 more

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in Clinical medicine & research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Emergency department early mortality model for patients admitted after presenting to a tertiary medical center emergency department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2025
    Article
  3. Elevated Cardiac Troponin I Level Associated to Cardiac Dysfunction in Burned Patients.Journal of burn care & research : official publication of the American Burn Association · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

R Jay WidmerDivision of Cardiology, Scott & White Heart Memorial Hospital, Baylor Scott & White Health, Temple, Texas, USA Robert.Widmer@BSWHealth.org.
Gibbs WilsonDivision of Internal Medicine, Scott & White Heart Memorial Hospital, Baylor Scott & White Health, Temple, Texas. USA.
Travis HanekeDivision of Internal Medicine, Scott & White Heart Memorial Hospital, Baylor Scott & White Health, Temple, Texas. USA.
Mary LeeDivision of Cardiology, Scott & White Heart Memorial Hospital, Baylor Scott & White Health, Temple, Texas, USA.
Jerry FanDivision of Internal Medicine, Scott & White Heart Memorial Hospital, Baylor Scott & White Health, Temple, Texas. USA.
Arthur DavisDivision of Internal Medicine, Scott & White Heart Memorial Hospital, Baylor Scott & White Health, Temple, Texas. USA.
Ethan FryDivision of Internal Medicine, Scott & White Heart Memorial Hospital, Baylor Scott & White Health, Temple, Texas. USA.
Kevin KurianDivision of Cardiology, Scott & White Heart Memorial Hospital, Baylor Scott & White Health, Temple, Texas, USA.
Jonathan UrbanczykDivision of Cardiology, Scott & White Heart Memorial Hospital, Baylor Scott & White Health, Temple, Texas, USA.
Jordan PotterDivision of Internal Medicine, Scott & White Heart Memorial Hospital, Baylor Scott & White Health, Temple, Texas. USA.
Matthew McMahonDivision of Internal Medicine, Scott & White Heart Memorial Hospital, Baylor Scott & White Health, Temple, Texas. USA.
Bryce RhodehouseDivision of Internal Medicine, Scott & White Heart Memorial Hospital, Baylor Scott & White Health, Temple, Texas. USA.
Joon J SongDivision of Biostatistics, Baylor University, Waco, Texas, USA.
Jeffrey B MichelDivision of Cardiology, Scott & White Heart Memorial Hospital, Baylor Scott & White Health, Temple, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTroponin values above the threshold established to diagnose acute myocardial infarction (AMI; >99th percentile) are commonly detected in patients with diagnoses other than AMI. The objective of this study was to compare inpatient mortality and 30-day readmission rate in patients with troponin I (TnI) above and below the 99th percentile in those with type 1 AMI and type 2 myocardial injury.

methodsBetween January 1, 2016 and December 31, 2016, there were 56,895 inpatient hospitalizations; of these 14,326 (25.2%) patients received troponin testing. We evaluated mortality and readmissions in the entire cohort based on the primary discharge International Classification of Diseases, Tenth Edition (ICD-10) diagnosis and grouped into type 1 AMI versus other diagnoses comprising the type 2 AMI group (including ICD-10 codes for congestive heart failure, sepsis, and other). Among those with TnI drawn, we evaluated in-hospital mortality and 30-day readmissions based on troponin values > 99th percentile (≥ 0.1 ng/ml).

resultsAmong the entire cohort, the inpatient mortality rate was significantly higher in those with TnI testing (5.0%, 95% CI 4.6%-5.3%) compared to those without testing (0.7%, 95% CI 0.6%-0.7%, P < 0.01). In the tested cohort 3,743 (26%) patients had troponin levels above the 99th percentile (> 0.1 ng/ml), and 10,583 (74%) had troponin levels below the 99th percentile (≤ 0.1 ng/ml). Comparing type 2 AMI with type 1 AMI and troponin testing, TnI values ≥ 0.1 ng/ml were associated with higher inpatient mortality (11.6% vs. 3.9%) and 30-day readmission rates (16.9% vs. 10.7%).

conclusionsA higher inpatient mortality and 30-day readmission rates were found in patients with type 2 AMI compared to type 1 AMI group.

Indexed as

Hospital MortalityInpatientsPatient ReadmissionAgedHumansMyocardial InfarctionTroponin ITroponin I30-day ReadmissionInpatient MortalityTroponinType 2 MI

Identifiers

PMID32060044
PMCPMC7428210

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.