Evidence map›Paper›PMID 32059981›Full record

ArticleThe Journal of allergy and clinical immunology2020

Primary prevention of asthma in high-risk children using HDM SLIT: Assessment at age 6 years.

Cherry Alviani, Graham Roberts, Frances Mitchell, Jane Martin, Zaraquiza Zolkipli, Louise J Michaelis, Pandurangan Vijayanand, Ramesh Kurukulaaratchy, S Hasan Arshad

Open access · greenAbstract readLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Clinical Practice Guideline: Immunotherapy for Inhalant Allergy.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
    Guideline
  2. Recent advances in allergen immunotherapy.Chinese medical journal · 2026
    Review
  3. Review
  4. Messenger RNA vaccines in the prevention of allergic diseases.The World Allergy Organization journal · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Allergen immunotherapy: past, present and future.Nature reviews. Immunology · 2023
    Review
  12. S3 guideline Allergy Prevention.Allergologie select · 2022
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Cherry AlvianiNIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom; Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton, United Kingdom; The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Isle of Wight, United Kingdom.
Graham RobertsNIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom; Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton, United Kingdom; Human Development in Health, University of Southampton Faculty of Medicine, Southampton, United Kingdom.
Frances MitchellThe David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Isle of Wight, United Kingdom.
Jane MartinNIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.
Zaraquiza ZolkipliDepartment of Allergy, Addenbrookes NHS Foundation Trust, Cambridge, United Kingdom.
Louise J MichaelisDepartment of Immunology, Infectious Diseases and Allergy, Great North Childrens' Hospital, Newcastle upon Tyne, United Kingdom.
Pandurangan VijayanandLa Jolla Institute for Immunology, La Jolla, Calif.
Ramesh KurukulaaratchyNIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom; Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton, United Kingdom; The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Isle of Wight, United Kingdom.
S Hasan ArshadNIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom; Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton, United Kingdom; The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Isle of Wight, United Kingdom. Electronic address: sha@soton.ac.uk.
University Hospital Southampton NHS Foundation Trust · GBGreat North Children's Hospital · GBLa Jolla Institute for Immunology · USSt Mary's Hospital · GB

Funding

Epigenome-wide association study of childhood asthmaR01AI121426 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI ARSHAD, SYED HASAN, PETERS, BJOERN · 2017 to 2021
$3.9M
Department of HealthNIAID NIH HHS R01 AI121426
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, SublingualAnimalsAsthmaChildDouble-Blind MethodFemaleHumansInfantMalePrimary PreventionProof of Concept StudyPyroglyphidaeSublingual Immunotherapy

Identifiers

PMID32059981
PMCPMC7282930
OpenAlexW3006049715

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.