Evidence map›Paper›PMID 32059949›Full record

ArticleAnalytical biochemistry2020

Fluorescent probe displacement assays reveal unique nucleic acid binding properties of human nudix enzymes.

Atreyei Ray, David N Frick

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Re-evaluation of Diadenosine Tetraphosphate (ApFrontiers in molecular biosciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Atreyei RayDepartment of Chemistry & Biochemistry, The University of Wisconsin- Milwaukee, Milwaukee, WI, 53217, USA.
David N FrickDepartment of Chemistry & Biochemistry, The University of Wisconsin- Milwaukee, Milwaukee, WI, 53217, USA. Electronic address: frickd@uwm.edu.
University of Wisconsin–Milwaukee · US

Funding

Antiviral potential of helicase inhibitorsR01AI088001 · NIAID · UNIVERSITY OF WISCONSIN MILWAUKEE · PI FRICK, DAVID N · 2010 to 2012
$1.1M
NIAID NIH HHS R01 AI088001
6 · The paper itself

Abstract

Nudix proteins are members of a large family of homologous enzymes that hydrolyze nucleoside diphosphates linked to other compounds. The substrates for a subset of Nudix enzymes are all nucleotides linked to RNA, like the m

Indexed as

Binding SitesDNADNA Repair EnzymesEscherichia coliFluorescent DyesHumansNudix HydrolasesPhosphoric Monoester HydrolasesPyrophosphatasesRecombinant ProteinsRNA8-oxodGTPaseDNADNA Repair EnzymesFluorescent DyesNudix HydrolasesNUDT12 protein, humanNUDT2 protein, humanPhosphoric Monoester HydrolasesPyrophosphatasesRecombinant ProteinsRNA7-Methlyguanosine triphosphate hydrolaseDe-capping enzymeDiphosphataseNADH pyrophosphataseNudixOrf257

Identifiers

PMID32059949
PMCPMC7087442
OpenAlexW3006095246

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.