Evidence map›Paper›PMID 32059793›Full record

ArticleCell chemical biology2020

Polynuclear Ruthenium Amines Inhibit K

Lianne Pope, Marco Lolicato, Daniel L Minor

Open access · bronzeAbstract read
In one paragraph

Article in Cell chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Structure-Function Relationships of KAdvances in experimental medicine and biology · 2026
    Review
  6. Structure of the human KNature structural & molecular biology · 2025
    Article
  7. Cryo-EM structure of the human THIK-1 K2P KNature structural & molecular biology · 2025
    Article
  8. A mechanism of CALHM1 ion channel gating.American journal of physiology. Cell physiology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Tick-Derived Peptide Blocks Potassium Channel TREK-1.International journal of molecular sciences · 2024
    Article
  14. Development of covalent chemogenetic KCell chemical biology · 2024
    Article
  15. Structure of the human KbioRxiv : the preprint server for biology · 2024
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lianne PopeCardiovascular Research Institute, University of California, San Francisco, CA 93858-2330, USA.
Marco LolicatoCardiovascular Research Institute, University of California, San Francisco, CA 93858-2330, USA.
Daniel L MinorCardiovascular Research Institute, University of California, San Francisco, CA 93858-2330, USA; Departments of Biochemistry and Biophysics, and Cellular and Molecular Pharmacology, University of California, San Francisco, CA 93858-2330, USA; California Institute for Quantitative Biomedical Research, University of California, San Francisco, CA 93858-2330, USA; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, CA 93858-2330, USA; Molecular Biophysics and Integrated Bio-imaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. Electronic address: daniel.minor@ucsf.edu.
University of California, San Francisco · USQB3 · US

Funding

Genetic and chemical biological studies of K2P structure, function, andmodulationR01MH093603 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DANIEL L MINOR · 2011 to 2026
$8.5M
RESEARCH TRAINING IN CHEMISTRY AND CHEMICAL BIOLOGYT32GM064337 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIK, CHARLES SCOTT · 2002 to 2021
$7.8M
NIGMS NIH HHS T32 GM064337NIMH NIH HHS R01 MH093603
6 · The paper itself

Abstract

The trinuclear ruthenium amine ruthenium red (RuR) inhibits diverse ion channels, including K

Indexed as

AminesAnimalsColoring AgentsCrystallography, X-RayMiceMolecular Docking SimulationPotassium Channels, Tandem Pore DomainRutheniumRuthenium CompoundsRuthenium RedAminesColoring Agentspotassium channel protein TREK-1Potassium Channels, Tandem Pore DomainRu 360RutheniumRuthenium CompoundsRuthenium RedCAP domainelectrophysiologyK2P channelKeystone inhibitor siteRu360ruthenium redX-ray crystallography

Identifiers

PMID32059793
PMCPMC7245552
OpenAlexW3006613614

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.