Evidence map›Paper›PMID 32059723›Full record

ArticleBMC complementary medicine and therapies2020

Chinese medicine Di-Huang-Yi-Zhi protects PC12 cells from H

Li-Min Zhang, Rong-Rong Zhen, Chao Gu, Tian-Li Zhang, Yue Li, Miao Jin, Bing Hu, Hong-Mei An

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in BMC complementary medicine and therapies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Li-Min ZhangDepartment of Neurology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Rong-Rong ZhenDepartment of Neurology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Chao GuDepartment of Neurology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Tian-Li ZhangDepartment of Neurology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Yue LiDepartment of Neurology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Miao JinDepartment of Neurology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Bing HuDepartment of Oncology, Institute of Traditional Chinese Medicine in Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China. beearhu@hotmail.com.ORCID 0000-0003-0810-6670
Hong-Mei AnDepartment of Science & Technology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China. lhsoatp@163.com.
Shanghai University of Traditional Chinese Medicine · CN

Funding

National Natural Science Foundation of China 81873246Natural Science Foundation of Shanghai (CN) 18ZR1439900Scientific and Technological Innovation Projects of Longhua Hospital CX201766
6 · The paper itself

Abstract

backgroundOxidative stress mediates the nerve injury during the pathogenesis of Alzheimer's disease (AD). Protecting against oxidative stress damage is an important strategy to prevent and treat AD. Di-Huang-Yi-Zhi (DHYZ) is a Chinese medicine used for the treatment of AD, but its mechanism remains unknown. This study is aimed to investigate the effect of DHYZ on H

methodsPC12 cells were treated with H

resultsThe results showed that DHYZ antagonized H

conclusionsThe present study suggested that DHYZ protected PC12 cells from H

Indexed as

AnimalsApoptosisDrugs, Chinese HerbalHydrogen PeroxideMAP Kinase Signaling SystemOxidative Stressp38 Mitogen-Activated Protein KinasesPC12 CellsRatsdi-huang-yi-zhiDrugs, Chinese HerbalHydrogen Peroxidep38 Mitogen-Activated Protein KinasesAlzheimer’s diseaseApoptosisChinese herbDi-Huang-Yi-ZhiOxidative stressPC12 cellsSignal transduction

Identifiers

PMID32059723
PMCPMC7076825
OpenAlexW3009870239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.