Evidence map›Paper›PMID 32059714›Full record

ArticleBMC oral health2020

Impact of non-surgical periodontal therapy on serum Resistin and periodontal pathogen in periodontitis patients with obesity.

Khairunnisa Md Tahir, Ainul Haliza Ab Malek, Rathna Devi Vaithilingam, Roslan Saub, Syarida Hasnur Safii, Mohammad Tariqur Rahman, Fathilah Abdul Razak, Aied M Alabsi, Nor Adinar Baharuddin

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02618486 (The Effects of Obesity on Non Surgical Periodontal Therapy), which is not on this map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02618486 nacompletednot on this map

The Effects of Obesity on Non Surgical Periodontal Therapy

TypeinterventionalSponsorUniversity of MalayaRan2014 to 2015Enrolled60ConditionsObese, Periodontal DiseaseArmsNon surgical periodontal therapy
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Khairunnisa Md TahirDepartment of Restorative Dentistry, Faculty of Dentistry, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia.
Ainul Haliza Ab MalekDepartment of Restorative Dentistry, Faculty of Dentistry, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia.
Rathna Devi VaithilingamDepartment of Restorative Dentistry, Faculty of Dentistry, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia.
Roslan SaubDepartment of Community Oral Health & Clinical Prevention, Faculty of Dentistry, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia.
Syarida Hasnur SafiiDepartment of Restorative Dentistry, Faculty of Dentistry, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia.
Mohammad Tariqur RahmanDean Office, Faculty of Dentistry, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia.
Fathilah Abdul RazakDepartment of Oral & Craniofacial Sciences, Faculty of Dentistry, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia.
Aied M AlabsiFaculty of Dentistry, MAHSA University, Jalan SP2, Bandar Saujana Putra, 42610, Jenjarom Kuala Langat, Selangor, Malaysia.
Nor Adinar BaharuddinDepartment of Restorative Dentistry, Faculty of Dentistry, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia. noradinar@um.edu.my.ORCID 0000-0001-6824-3744
University of Malaya · MYAirlangga University · IDMahsa University · MY

Funding

Institut Pengurusan dan Pemantauan Penyelidikan, Universiti Malaya UMRG, RP031-14HTMPostgraduate Research Fund PPPC PG025-2014APostgraduate Research Fund PPPC PPPC/C1-2015/DGL/22
6 · The paper itself

Abstract

backgroundNon-surgical periodontal therapy (NSPT) known as gold standard treatment in managing periodontitis. The aim of this study was to investigate the response of NSPT in periodontitis subjects who were obese. Clinical parameters of periodontitis, changes in serum resistin and periodontal pathogens in subgingival plaque were compared before and after NSPT in periodontitis subjects who were obese and with normal weight.

methodsA total of 48 periodontitis subjects (obese, n = 18; normal weight, n = 30) were recruited (hereafter will be referred as participants) to participate into a prospective, before and after clinical trial. Obesity status is defined by body mass index (BMI) criteria (obese: ≥30 kg/ m

resultsFollowing NSPT, means VPI and GBI showed significant improvement between obese and normal weight groups (p <  0.05), but no difference in means PPD and CAL was observed between groups. Obesity remained as a predictor for VPI and GBI after adjusting for smoking habit. No significant difference was observed in serum resistin level and mean counts for P. gingivalis, T. forsythia, and P. intermedia between obese and normal weight groups following NSPT.

conclusionsRegardless of obesity status, NSPT has a significant impact on VPI and GBI in periodontitis subjects. However, the impact of NSPT towards serum resistin and periodontal pathogens was non-significant in those with periodontitis.

trial registrationThis study followed the Consolidation Standards of Reporting Trials Statement and retrospectively registered on 26/11/2015 at clinicaltrials.gov (No. NCT02618486).

Indexed as

Chronic PeriodontitisDental Plaque IndexFemaleHumansMaleObesityPeriodontal Attachment LossProspective StudiesResistinResistinCytokineObesePeriodontal pathogensPeriodontal therapyPeriodontitis

Identifiers

PMID32059714
PMCPMC7023789
OpenAlexW3008924544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.