Evidence map›Paper›PMID 32059708›Full record

ArticleBMC nephrology2020

Albumin-globulin ratio and mortality in patients on peritoneal dialysis: a retrospective study.

Fenfen Peng, Lingzhi Sun, Ting Chen, Yan Zhu, Weidong Zhou, Peilin Li, Yihua Chen, Yiyi Zhuang, Qianyin Huang, Haibo Long

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  5. Diagnostic work-up in periprosthetic joint infections of the knee: can the albumin-to-globulin ratio be a screening tool?Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025
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  11. Associations between liver function parameters and poor clinical outcomes in peritoneal dialysis patients.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2023
    Review
  12. Association of serum globulin with all-cause mortality in incident hemodialysis patients.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Fenfen PengDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Lingzhi SunDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Ting ChenDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Yan ZhuDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Weidong ZhouDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Peilin LiDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Yihua ChenDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Yiyi ZhuangDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Qianyin HuangDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China. huangqy@whu.edu.cn.
Haibo LongDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China. Longhb1966@163.com.ORCID 0000-0001-6891-8916
Zhujiang Hospital · CN

Funding

National Natural Science Foundation of China 81600624National Natural Science Foundation of China 81673792National Natural Science Foundation of China 81704134National Natural Science Foundation of China 81873346National Natural Science Foundation of China 81900607National Natural Science Foundation of China U1801288Natural Science Foundation of Guangdong Province, China 2017A030313708Science and Technology Planning Project of Guangdong Province, China 2017A020215158Science and Technology Planning Project of Guangzhou, China 201707010286
6 · The paper itself

Abstract

backgroundAlbumin-globulin ratio (AGR), a variable based on serum albumin and non-albumin proteins, has been demonstrated as a predictor of mortality in patients with malignant neoplasm. The aim of this study was to evaluate the prognostic value of AGR on peritoneal dialysis (PD) patients.

methodsWe retrospectively analyzed 602 incident PD patients from January 1st, 2008, to December 31st, 2017, at our center and followed them until December 31st, 2018. Kaplan-Meier curves and multivariate Cox regression models were applied to analyze the association between AGR and all-cause of mortality and cardiovascular mortality.

resultsThe median follow-up time was 32.17 (interquartile range = 32.80) months. During follow-up, 131 (21.8%) patients died, including 57 patients (43.5%) who died due to cardiovascular diseases. Kaplan-Meier curves showed that patients with AGR > 1.26 had better rates of survival than those with AGR ≤ 1.25 (p < 0.001). After adjusting for potential confounders, the lower AGR level was significantly associated with an increased all-cause and cardiovascular mortality [hazard ratio (HR): 1.57, 95% confidence interval (CI): 1.07-2.32, p = 0.022 and HR: 2.01, 95% CI: 1.10-3.69, p = 0.023 respectively].

conclusionsPatients with a low AGR level had an increased all-cause and cardiovascular mortality. AGR may be a useful index in identifying patients on PD at risk for CVD and all-cause of mortality.

Indexed as

Cardiovascular DiseasesFemaleHumansMaleMiddle AgedPeritoneal DialysisPrognosisProportional Hazards ModelsRetrospective StudiesSerum AlbuminSerum GlobulinsSerum AlbuminSerum GlobulinsAlbumin-globulin ratioMortalityPeritoneal dialysis

Identifiers

PMID32059708
PMCPMC7023751
OpenAlexW3006125254

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.