Evidence map›Paper›PMID 32059689›Full record

ArticleItalian journal of pediatrics2020

Survey of PDA management in very low birth weight infants across Italy.

Benjamim Ficial, Iuri Corsini, Stefano Fiocchi, Federico Schena, Irma Capolupo, Rosa Maria Cerbo, Manuela Condò, Daniela Doni, Simona La Placa, Salvatore Porzio and 4 more

Abstract read
In one paragraph

Article in Italian journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  9. Oral Versus Intravenous Medications for Treatment of Patent Ductus Arteriosus in Preterm Neonates: A Cost-Saving Initiative.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Benjamim FicialNeonatal Intensive Care Unit, Azienda Ospedaliera Universitaria Integrata di Verona, P.le Stefani 1, 37126, Verona, Italy. benjamim.ficial@gmail.com.ORCID http://orcid.org/0000-0001-6056-5757
Iuri CorsiniDivision of Neonatalogy, Careggi University Hospital of Florence, Florence, Italy.
Stefano FiocchiNeonatologia e Terapia Intensiva Neonatale, Ospedale Valduce, Como, Italy.
Federico SchenaNeonatal Intensive Care Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy.
Irma CapolupoNeonatal Intensive Care Unit, Ospedale Pediatrico Bambino Gesù, Rome, Italy.
Rosa Maria CerboNeonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Manuela CondòNeonatal Intensive Care Unit, Ospedale A. Manzoni, Lecco, Italy.
Daniela DoniNeonatal Intensive Care Unit, FMBBM San Gerardo, Monza, Italy.
Simona La PlacaNeonatal Intensive Care Unit, AOUP Giaccone, Palermo, Italy.
Salvatore PorzioNeonatal Section, San Michele Hospital, Maddaloni, NA, Italy.
Katia RossiNeonatal Intensive Care Unit, Policlinico di Modena, Modena, Italy.
Sabrina SalvadoriNeonatal Intensive Care Unit, Azienda Ospedaliera-Università di Padova, Padova, Italy.
Marilena SavoiaNeonatal Intensive Care Unit, Azienda Ospedaliera Universitaria S Maria della Misericordia, Udine, Italy.
On the behalf of the Italian Study Group of Neonatal Cardiology of the Italian Society of Neonatology

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe optimal management of PDA in very low birth weight (VLBW) infants is still controversial. Aim of our study was to investigate the management of PDA in the Italian neonatal intensive care units (NICU).

methodsWe conducted an on-line survey study from June to September 2017. A 50-items questionnaire was developed by the Italian Neonatal Cardiology Study Group and was sent to Italian NICUs.

resultsThe overall response rate was 72%. Diagnosis of PDA was done by neonatologists, cardiologists or both (62, 12 and 28% respectively). PDA significance was assessed by a comprehensive approach in all centers, although we found a heterogeneous combination of parameters and cut-offs used. None used prophylactic treatment. 19% of centers treated PDA in the first 24 h, 60% after the first 24 h, following screening echocardiography or clinical symptoms, 18% after the first 72 h and 2% after the first week. In the first course of treatment ibuprofen, indomethacin and paracetamol were used in 87, 6 and 7% of centers respectively. Median of surgical ligation was 3% (1-6%).

conclusionsSignificant variations exist in the management of PDA in Italy. Conservative strategy and targeted treatment to infants older than 24 h with echocardiographic signs of hemodynamic significance seemed to be the most adopted approach.

Indexed as

Intensive Care, NeonatalPractice Patterns, Physicians'Cross-Sectional StudiesDuctus Arteriosus, PatentEchocardiographyHumansInfant, NewbornInfant, Very Low Birth WeightIntensive Care Units, NeonatalItalyProspective StudiesSurveys and QuestionnairesNeonatologist performed echocardiographyPDA managementPreterm infantsSurvey

Identifiers

PMID32059689
PMCPMC7023762

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.