Evidence map›Paper›PMID 32059672›Full record

ReviewMolecular cancer2020

Translation and functional roles of circular RNAs in human cancer.

Ming Lei, Guantao Zheng, Qianqian Ning, Junnian Zheng, Dong Dong

Open access · goldAbstract readReview
In one paragraph

Review in Molecular cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 434 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
434citing papers in PubMed, 1 pooled it
44.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

434 citing papers in PubMed, 1 synthesis or guideline pooled it, 954 citations in OpenAlex.

  1. MicroRNA expression in osteoarthritis: a meta-analysis.Clinical and experimental medicine · 2023
    Pooled it
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374 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ming LeiCancer Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Guantao ZhengCancer Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Qianqian NingCancer Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Junnian ZhengCancer Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China. jnzheng@xzhmu.edu.cn.
Dong DongCancer Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China. ddong@xzhmu.edu.cn.
Xuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs) are a new class of non-coding RNAs formed by covalently closed loops through backsplicing. Recent methodologies have enabled in-depth characterization of circRNAs for identification and potential functions. CircRNAs play important roles in various biological functions as microRNA sponges, transcriptional regulators and combining with RNA binding proteins. Recent studies indicated that some cytoplasmic circRNAs can be effectively translated into detectable peptides, which enlightened us on the importance of circRNAs in cellular physiology function. Internal Ribosome Entry site (IRES)- and N

Indexed as

Gene Expression Regulation, NeoplasticAnimalsBiomarkers, TumorHumansNeoplasmsRNA-Binding ProteinsRNA, CircularBiomarkers, TumorRNA-Binding ProteinsRNA, CircularBiomarkerCancerCircular RNAFunctionTranslation

Identifiers

PMID32059672
PMCPMC7023758
OpenAlexW3006786463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.