Evidence map›Paper›PMID 32059539›Full record

ArticleBiomolecules2020

Hyperoxia Alters Ultrastructure and Induces Apoptosis in Leukemia Cell Lines.

David De Bels, Frauke Tillmans, Francis Corazza, Mariano Bizzari, Peter Germonpre, Peter Radermacher, Keziban Günce Orman, Costantino Balestra

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  7. Review
  8. Review
  9. Article
  10. Oxygen: A Stimulus, Not "Only" a Drug.Medicina (Kaunas, Lithuania) · 2021
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

David De BelsEnvironmental & Occupational Physiology Laboratory, Haute Ecole Bruxelles-Brabant, 1180 Brussels, Belgium.
Frauke TillmansEnvironmental & Occupational Physiology Laboratory, Haute Ecole Bruxelles-Brabant, 1180 Brussels, Belgium.ORCID 0000-0002-2159-0834
Francis CorazzaTranslational Research Laboratory, Université Libre de Bruxelles, 1050 Brussels, Belgium.
Mariano BizzariExperimental Medicine Llaboratory, La Sapienza University of Rome, 00185 Rome, Italy.
Peter GermonpreEnvironmental & Occupational Physiology Laboratory, Haute Ecole Bruxelles-Brabant, 1180 Brussels, Belgium.
Peter RadermacherClinic of Anesthesiology, Section Anaesthesiological Pathophysiology and Process Development, University of Ulm, 89081 Ulm, Germany.
Keziban Günce OrmanDepartment of Computer Engineering, Galatasaray University, Ortakoy, Istanbul 34349, Turkey.
Costantino BalestraEnvironmental & Occupational Physiology Laboratory, Haute Ecole Bruxelles-Brabant, 1180 Brussels, Belgium.
Université Libre de Bruxelles · BEUniversität Ulm · DEEuropean Research Council · BEGalatasaray University · TRSapienza University of Rome · IT

Funding

Marie Curie 2016
6 · The paper itself

Abstract

Oxygenation conditions are crucial for growth and tumor progression. Recent data suggests a decrease in cancer cell proliferation occurring after exposure to normobaric hyperoxia. Those changes are associated with fractal dimension. The purpose of this research was to study the impact of hyperoxia on apoptosis and morphology of leukemia cell lines. Two hematopoietic lymphoid cancer cell lines (a T-lymphoblastoid line, JURKAT and a B lymphoid line, CCRF-SB) were tested under conditions of normobaric hyperoxia (FiO

Indexed as

ApoptosisHyperoxiaB-LymphocytesCaspase 3Cell CycleCell Line, TumorCell ProliferationFractalsHumansJurkat CellsLeukemiaOxygenSoftwareT-LymphocytesCASP3 protein, humanCaspase 3Oxygenapoptosiscaspasefractalshyperoxialeukemianormobaric oxygen paradox

Identifiers

PMID32059539
PMCPMC7072400
OpenAlexW3006289939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.