Evidence map›Paper›PMID 32059495›Full record

ArticleMolecules (Basel, Switzerland)2020

Metronidazole and Secnidazole Carbamates: Synthesis, Antiprotozoal Activity, and Molecular Dynamics Studies.

Genaro Rocha-Garduño, Norma Angélica Hernández-Martínez, Blanca Colín-Lozano, Samuel Estrada-Soto, Emanuel Hernández-Núñez, Fernando Daniel Prieto-Martínez, José L Medina-Franco, Juan Bautista Chale-Dzul, Rosa Moo-Puc, Gabriel Navarrete-Vázquez

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  3. Anti-Pharmaceuticals (Basel, Switzerland) · 2025
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  8. Article
  9. Synthesis and antimicrobial activity of 1Beilstein journal of organic chemistry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Genaro Rocha-GarduñoFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos 62209, México.
Norma Angélica Hernández-MartínezFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos 62209, México.
Blanca Colín-LozanoFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos 62209, México.
Samuel Estrada-SotoFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos 62209, México.
Emanuel Hernández-NúñezCátedra CONACyT, Departamento de Recursos del Mar, Centro de Investigación y de Estudios Avanzados del IPN, Unidad Mérida, Yucatán 97310, México.
Fernando Daniel Prieto-MartínezFacultad de Química, Departamento de Farmacia, Universidad Nacional Autónoma de México, México City 04510, México.
José L Medina-FrancoFacultad de Química, Departamento de Farmacia, Universidad Nacional Autónoma de México, México City 04510, México.
Juan Bautista Chale-DzulLaboratorio de Apoyo a la Vigilancia Epidemiológica, Hospital de Especialidades 1, Centro Médico Nacional Ignacio García Téllez, Instituto Mexicano del Seguro Social, Mérida 97150, Yucatán, México.
Rosa Moo-PucUnidad de Investigación Médica Yucatán, Unidad Médica de Alta Especialidad, Centro Médico Nacional Ignacio García Téllez, Instituto Mexicano del Seguro Social, Mérida 97000, Yucatán, México.
Gabriel Navarrete-VázquezFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos 62209, México.
Universidad Autónoma del Estado de Morelos · MXMexican Social Security Institute · MXUniversidad Nacional Autónoma de México · MXInstituto Politécnico Nacional · MX

Funding

Consejo Nacional de Ciencia y Tecnología 253814
6 · The paper itself

Abstract

We prepared a series of 10 carbamates derivatives based on two common antiprotozoal drugs: metronidazole (

Indexed as

Antiprotozoal AgentsCarbamatesGiardia lambliaGiardiasisMetronidazoleTrichomonas InfectionsTrichomonas vaginalisAntiprotozoal AgentsCarbamatesMetronidazolesecnidazolecarbamatesmetronidazolemolecular dynamicsparasitessecnidazole

Identifiers

PMID32059495
PMCPMC7071106
OpenAlexW3006640919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.