Evidence map›Paper›PMID 32059479›Full record

ArticleMolecules (Basel, Switzerland)2020

Synthesis and Antibacterial Activity of Difluoromethyl Cinnamoyl Amides.

Mario David Martínez, Diego Ariel Riva, Cybele Garcia, Fernando Javier Durán, Gerardo Burton

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mario David MartínezCONICET-Universidad de Buenos Aires, UMYMFOR, Buenos Aires, Argentina.
Diego Ariel RivaCONICET-Universidad de Buenos Aires, IQUIBICEN, Buenos Aires C1428EGA, Argentina.
Cybele GarciaCONICET-Universidad de Buenos Aires, IQUIBICEN, Buenos Aires C1428EGA, Argentina.
Fernando Javier DuránCONICET-Universidad de Buenos Aires, UMYMFOR, Buenos Aires, Argentina.
Gerardo BurtonCONICET-Universidad de Buenos Aires, UMYMFOR, Buenos Aires, Argentina.

Funding

Consejo Nacional de Investigaciones Científicas y Técnicas 11220110100896CO
6 · The paper itself

Abstract

Series of novel amides of isoferulic acid, where the phenolic hydroxyl was replaced by a difluoromethyl group, were synthesized and their in vitro antibacterial activities assayed against fourteen bacterial strains (six Gram-positive and eight Gram-negative). A one-pot methodology was developed to obtain the 3'-(difluoromethyl)-4'-methoxycinnamoyl amides using Deoxofluor

Indexed as

AmidesAnti-Bacterial AgentsAntineoplastic AgentsCell ProliferationHep G2 CellsHumansMicrobial Sensitivity TestsMycobacterium smegmatisStructure-Activity RelationshipAmidesAnti-Bacterial AgentsAntineoplastic Agentsantibacterialcinnamic acid amidesdifluoromethyl group

Identifiers

PMID32059479
PMCPMC7070587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.