Evidence map›Paper›PMID 32059373›Full record

ArticleInternational journal of molecular sciences2020

Dynamic Changes in pStat3 are Involved in Meiotic Spindle Assembly in Mouse Oocytes.

Seiki Haraguchi, Mitsumi Ikeda, Satoshi Akagi, Yuji Hirao

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. STAT3 Is an Upstream Regulator ofInternational journal of molecular sciences · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Seiki HaraguchiAnimal Biotechnology Unit, Division of Animal Sciences, Institute of Agrobiological Sciences, NARO, 2 Ikenodai, Tsukuba, Ibaraki 305-0901, Japan.
Mitsumi IkedaAnimal Biotechnology Unit, Division of Animal Sciences, Institute of Agrobiological Sciences, NARO, 2 Ikenodai, Tsukuba, Ibaraki 305-0901, Japan.
Satoshi AkagiEmbryo Production Research Unit, Division of Animal Breeding and Reproduction Research, Institute of Livestock and Grassland Science, NARO, 2 Ikenodai, Tsukuba, Ibaraki 305-0901, Japan.
Yuji HiraoEmbryo Production Research Unit, Division of Animal Breeding and Reproduction Research, Institute of Livestock and Grassland Science, NARO, 2 Ikenodai, Tsukuba, Ibaraki 305-0901, Japan.
Institute of Agrobiological Sciences · JPInstitute of Livestock and Grassland Science · JP

Funding

National Agriculture and Food Research Organization CJN13HW0, CJN41H54, NIP-H29.
6 · The paper itself

Abstract

The signal transducer and activator of transcription 3 (Stat3) is activated upon phosphorylation at Y705 (pStat3) and serves the dual function of signal transduction and transcription activation. Our previous study suggested that pStat3 is functional during oocyte maturation when transcription is silenced. Therefore, we speculated that pStat3 serves other functions. Immunocytochemical analysis revealed that pStat3 emerges at microtubule asters and spindle and is subsequently localized at the spindle poles along with pericentrin during mouse oocyte maturation. Both Stat3 and pStat3 proteins were detected in conditionally knocked out

Indexed as

AnimalsAntigensAromatase InhibitorsFemaleGene Expression Regulation, DevelopmentalGrowth InhibitorsIntercellular Signaling Peptides and ProteinsMeiosisMiceMice, Inbred C57BLMice, KnockoutOocytesPhosphorylationSpindle ApparatusSTAT3 Transcription FactorTranscriptomeAntigensAromatase InhibitorsGrowth InhibitorsIntercellular Signaling Peptides and Proteinsintraovarian peptidespericentrinStat3 protein, mouseSTAT3 Transcription FactormeiosisMTOCsoocyte maturationpStat3spindle assemblyStat3

Identifiers

PMID32059373
PMCPMC7072877
OpenAlexW2999450208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.