Evidence map›Paper›PMID 32059363›Full record

ArticleInternational journal of molecular sciences2020

Mathematical Model of ATM Activation and Chromatin Relaxation by Ionizing Radiation.

Yongfeng Li, Francis A Cucinotta

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. TRIM28 in cancer and cancer therapy.Frontiers in genetics · 2024
    Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yongfeng LiDivision of Space and Life Sciences, USRA (Retired), Houston, TX 77574, USA.
Francis A CucinottaDepartment of health Physics and Diagnostic Sciences, University of Nevada Las Vegas, Las Vegas, NV 89154, USA.
University of Nevada, Las Vegas · US

Funding

Department of Energy DE-AI02-10ER64969
6 · The paper itself

Abstract

We propose a comprehensive mathematical model to study the dynamics of ionizing radiation induced Ataxia-telangiectasia mutated (ATM) activation that consists of ATM activation through dual mechanisms: the

Indexed as

Models, TheoreticalRadiation, IonizingActivating Transcription Factor 2Ataxia TelangiectasiaAtaxia Telangiectasia Mutated ProteinsBleomycinCell Cycle ProteinsChromatinDNA Breaks, Double-StrandedDNA DamageHumansOxidative StressPhosphorylationSignal TransductionSystems BiologyTripartite Motif-Containing Protein 28Activating Transcription Factor 2Ataxia Telangiectasia Mutated ProteinsATF2 protein, humanATM protein, humanBleomycinCell Cycle ProteinsChromatinTRIM28 protein, humanTripartite Motif-Containing Protein 28ATM signaling pathwaybiophysics modelschromatin relaxationdouble strand break repairIonizing radiationoxidative stressspace radiationsystems biology

Identifiers

PMID32059363
PMCPMC7072770
OpenAlexW3006493921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.