Evidence map›Paper›PMID 32059230›Full record

ArticlePediatric research2020

Placenta and perinatal brain injury: the gateway to individualized therapeutics and precision neonatal medicine.

Lauren L Jantzie, Shenandoah Robinson

Abstract readComment
In one paragraph

Article in Pediatric research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Lauren L JantzieDepartment of Pediatrics, Johns Hopkins Children's Center, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Shenandoah RobinsonDepartment of Neurology, Johns Hopkins Children's Center, Johns Hopkins School of Medicine, Baltimore, MD, USA. srobin81@jhmi.edu.

Funding

Placental Mediated Mechanisms of Perinatal Brain InjuryR01HL139492 · NHLBI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI JANTZIE, LAUREN LEIGH COONEY · 2018 to 2021
$1.6M
NHLBI NIH HHS R01 HL139492
6 · The paper itself

Abstract

Wu and colleagues analyzed the placental pathology from a subset of the neonates in the NEATO trial who had reports available and correlated the placental pathology findings with outcomes. This study highlights the importance of placental pathology, and its potential to bring precision medicine to critically-ill neonates. Placental pathology will likely aid stratification of neonates for clinical trials and accelerate progress for neurorepair.

Indexed as

Brain InjuriesErythropoietinHypoxia-Ischemia, BrainBrainFemaleHumansInfant, NewbornMagnetic Resonance ImagingPlacentaPrecision MedicinePregnancyErythropoietin

Identifiers

PMID32059230
PMCPMC10097459

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.