ArticlePloS one2020
Reduction of variability for the assessment of side effects of toxicants on honeybees and understanding drivers for colony development.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Evaluating efficacy of oxytetracycline, lincomycin, and tylosin for treatment of clinical European foulbrood disease.Journal of insect science (Online) · 2026Article
- A technical semi-field methodology to measure the effect of nutrition on honey bee brood rearing.The Journal of experimental biology · 2026Article
- Brood indicators are an early warning signal of honey bee colony loss-a simulation-based study.PloS one · 2024Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The statistical power of studies for the assessment of side effects of toxicants on honeybees conducted according to current guidelines is often limited. A new test design and modified field methods have therefore been developed to decrease uncertainty and variability and to be able to detect small effects. The new test design comprises a monitoring phase (before the tunnel phase) for the selection of honeybee colonies and modified methods, which include assessments of colony strength, an evaluation of the cell content of all cells of hives using photos and digital analysis, and the use of video recordings for the assessment of foraging activity and forager mortality. With the proposed new study design and the modified field methods variability between hives was considerably reduced, which resulted in a marked reduction of the minimum detectable difference (MDD). This makes it possible to address the Specific Protection Goals defined by the European Food Safety Authority and to gain unprecedented insight into the development of hives and driving factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.