ArticleExperimental neurology2020
Bioenergetic restoration and neuroprotection after therapeutic targeting of mitoNEET: New mechanism of pioglitazone following traumatic brain injury.
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Article in Experimental neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
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Who cites it
33 citing papers in PubMed, 58 citations in OpenAlex.
- Cell-based polygenic risk scores predict clinical progression and prioritize network-based therapeutic targets in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Mitochondrial CISD1 Modulates Microglial Metabolic Reprogramming to Drive Stress Susceptibility in Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Pioglitazone modulates metabolic adaptation and peripheral nerve regeneration after injury.Molecular neurodegeneration · 2025Article
- Article
- Spatiotemporal diversity in molecular and functional abnormalities in the mdx dystrophic brain.Molecular medicine (Cambridge, Mass.) · 2025Article
- Potential Mitochondria-Related Key Genes in Post-Traumatic Stress Disorder Analyzed by Machine Learning Methods.Neuropsychiatric disease and treatment · 2025Article
- Loss of the mitochondrial protein mitoNEET in mice is associated with cognitive impairments and increased neuroinflammation.Journal of Alzheimer's disease : JAD · 2025Article
- The emerging role of cuproptosis in spinal cord injury.Frontiers in immunology · 2025Review
- Suppression ofmicroPublication biology · 2025Article
- mTOR inhibition enhances synaptic and mitochondrial function in Alzheimer's disease in an APOE genotype-dependent manner.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- From spreading depolarization to blood-brain barrier dysfunction: navigating traumatic brain injury for novel diagnosis and therapy.Nature reviews. Neurology · 2024Review
- NL-1 Promotes PINK1-Parkin-Mediated Mitophagy Through MitoNEET Inhibition in Subarachnoid Hemorrhage.Neurochemical research · 2024Article
- MitoNEET Provides Cardioprotection via Reducing Oxidative Damage and Conserving Mitochondrial Function.International journal of molecular sciences · 2023Review
- Fundamental Neurochemistry Review: Microglial immunometabolism in traumatic brain injury.Journal of neurochemistry · 2023Review
- Development of a fluorescence screening assay for binding partners of the iron-sulfur mitochondrial protein mitoNEET.Bioorganic & medicinal chemistry letters · 2023Article
- Synergistic Effect ofNutrients · 2023Article
- Pioglitazone restores mitochondrial function but does not spare cortical tissue following mild brain contusion.Brain communications · 2023Article
- Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma.Mitochondrion · 2023Review
- Role of estrogen in the regulation of central and peripheral energy homeostasis: from a menopausal perspective.Therapeutic advances in endocrinology and metabolism · 2023Review
- The Intriguing mitoNEET: Functional and Spectroscopic Properties of a Unique [2Fe-2S] Cluster Coordination Geometry.Molecules (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Heather M YonutasSpinal Cord & Brain Injury Research Center, University of Kentucky, Lexington, KY 40536, USA; Department of Neuroscience, University of Kentucky, Lexington, KY 40536, USA. Electronic address: heather.yonutas@yahoo.com.
W Brad HubbardSpinal Cord & Brain Injury Research Center, University of Kentucky, Lexington, KY 40536, USA; Department of Neuroscience, University of Kentucky, Lexington, KY 40536, USA; Lexington VA Healthcare System, Lexington, KY 40502, USA. Electronic address: bradhubbard@uky.edu.
Jignesh D PandyaSpinal Cord & Brain Injury Research Center, University of Kentucky, Lexington, KY 40536, USA; Currently Research Biologist, Brain Trauma Neuroprotection and Neurorestoration (BTNN) Branch, Walter Reed Army Institute of Research (WRAIR), Silver Spring, MD 20910, USA. Electronic address: jignesh.d.pandya.civ@mail.mil.
Hemendra J VekariaSpinal Cord & Brain Injury Research Center, University of Kentucky, Lexington, KY 40536, USA; Department of Neuroscience, University of Kentucky, Lexington, KY 40536, USA. Electronic address: hemendravekaria@uky.edu.
Werner J GeldenhuysDepartment of Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown 26501, USA. Electronic address: werner.geldenhuys@hsc.wvu.edu.
Patrick G SullivanSpinal Cord & Brain Injury Research Center, University of Kentucky, Lexington, KY 40536, USA; Department of Neuroscience, University of Kentucky, Lexington, KY 40536, USA; Lexington VA Healthcare System, Lexington, KY 40502, USA. Electronic address: patsullivan@uky.edu.
University of Kentucky · USUniversity of Kentucky HealthCare · USWest Virginia University · US
Funding
West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Anne Courtney DeVries · 2012 to 2026
$81.0MKentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2MWest Virginia University Stroke COBREP20GM109098 · NIGMS · WEST VIRGINIA UNIVERSITY · PI DEVRIES, ANNE COURTNEY · 2014 to 2024
$24.5MKentucky Center for Clinical and Translational ScienceUL1TR000117 · NCATS · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2012 to 2015
$13.3MEssential Siemens Prisma Fit Upgrade for the University of Kentucky 3T Research ScannerS10OD023573 · OD · UNIVERSITY OF KENTUCKY · PI SMITH, CHARLES DENNIS · 2017 to 2017
$813kInvestigating the Role of Pioglitazone, mitoNEET and Mitochondria following TBIF31NS086395 · NINDS · UNIVERSITY OF KENTUCKY · PI YONUTAS, HEATHER · 2014 to 2015
$48kTargeting mitostasis via activation of mitochondrial biogenesis after TBII01BX003405 · VA · VA MEDICAL CENTER - LEXINGTON, KY · PI SULLIVAN, PATRICK G · 2017 to 2025
–BLRD VA I01 BX003405NCATS NIH HHS UL1 TR000117NCATS NIH HHS UL1 TR001998NIGMS NIH HHS P20 GM109098NIGMS NIH HHS U54 GM104942NIH HHS S10 OD023573NINDS NIH HHS F31 NS086395
Abstract
Mitochondrial dysfunction is a pivotal event in many neurodegenerative disease states including traumatic brain injury (TBI) and spinal cord injury (SCI). One possible mechanism driving mitochondrial dysfunction is glutamate excitotoxicity leading to Ca
Indexed as
AnimalsBrain Injuries, TraumaticDisease Models, AnimalEnergy MetabolismIron-Binding ProteinsMaleMembrane ProteinsMiceMice, KnockoutMitochondriaNeuroprotectionNeuroprotective AgentsPioglitazoneRatsRats, Sprague-DawleyIron-Binding ProteinsMembrane ProteinsmitoNEET protein, mouseNeuroprotective AgentsPioglitazoneBeam walkCalcium overloadControlled cortical impactMitochondrial bioenergeticsNL-1Novel object recognitionSeahorse
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.