Evidence map›Paper›PMID 32057507›Full record

ArticleAnais brasileiros de dermatologia

Worse survival of invasive melanoma patients in men and "de novo" lesions.

Mara Huffenbaecher Giavina-Bianchi, Cyro Festa-Neto, Jose Antonio Sanches, Monica La Porte Teixeira, Bernadette Cunha Waldvogel

Abstract read
In one paragraph

Article in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mara Huffenbaecher Giavina-BianchiDepartment of Dermatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil. Electronic address: marahgbianchi@gmail.com.
Cyro Festa-NetoDepartment of Dermatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Jose Antonio SanchesDepartment of Dermatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Monica La Porte TeixeiraDepartment of Data Information Analysis and Dissemination, Fundação Sistema Estadual de Análise de Dados, São Paulo, SP, Brazil.
Bernadette Cunha WaldvogelDepartment of Data Information Analysis and Dissemination, Fundação Sistema Estadual de Análise de Dados, São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence and mortality of melanoma is increasing in many countries, including Brazil. Survival studies are still scarce in our country, but much needed to know and address this problem better.

objectiveTo analyze the disease-specific survival of patients with invasive melanoma and to correlate it with clinical and histopathological variables.

methodsRetrospective cohort analysis of 565 cases of invasive melanoma in a tertiary hospital with the objective of testing variables that could be associated with a worse prognosis, such as gender, phototype, thickness, histological type and presence of pre-existing clinical lesion at the site of the tumor.

resultsThe worst survival rates were significantly associated with thicker tumors (p<0.001), male sex (p=0.014), high phototype (p=0.047), nodular melanoma (p=0.024) and "de novo" lesions (p=0.005). When all variables were adjusted for melanoma thickness, male patients (p=0.011) and "de novo" melanomas (p=0.025) remained associated with worse survival. STUDY LIMITATIONS: Retrospective study of a single tertiary hospital.

conclusionsAlthough the causes are still unknown, melanoma-specific survival was statistically worse for males and for "de novo" melanomas even after adjustment of tumor thickness.

Indexed as

AdolescentAdultAgedAged, 80 and overAge FactorsBrazilChildChild, PreschoolDisease-Free SurvivalFemaleHumansInfantMaleMelanomaMiddle AgedProportional Hazards ModelsBrazilEpidemiologyMelanomaSurvival

Identifiers

PMID32057507
PMCPMC7175044

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.