ArticleThe Journal of thoracic and cardiovascular surgery2020
Role of surgeon intuition and computer-aided design in Fontan optimization: A computational fluid dynamics simulation study.
Article in The Journal of thoracic and cardiovascular surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Altered caval flow and wall shear stress in single ventricle circulation: insights from ferumoxytol-enhanced 4D flow MRI.European heart journal. Imaging methods and practice · 2026Article
- Venous Measurements as Predictors of Long-Term Fontan Complications: A Single-Center Echocardiographic Study.Journal of clinical practice and research · 2026Article
- Fontan Surgical Planning: Numerical Simulations Reveal Efficient Geometries Predicting Post-Surgical Outcomes.Brazilian journal of cardiovascular surgery · 2025Article
- Parameter selection and optimization of a computational network model of blood flow in single-ventricle patients.Journal of the Royal Society, Interface · 2025Article
- Automatic Laplacian-based shape optimization for patient-specific vascular grafts.Computers in biology and medicine · 2025Article
- HVSMR-2.0: A 3D cardiovascular MR dataset for whole-heart segmentation in congenital heart disease.Scientific data · 2024Article
- Tetralogy of Fallot regurgitation energetics and kinetics: an intracardiac flow analysis of the right ventricle using computational fluid dynamics.The international journal of cardiovascular imaging · 2024Article
- Virtual Planning and Patient-Specific Graft Design for Aortic Repairs.Cardiovascular engineering and technology · 2024Article
- The convergent cavopulmonary connection: A novel and efficient configuration of Fontan to accommodate mechanical support.JTCVS open · 2023Article
- A computational study of aortic reconstruction in single ventricle patients.Biomechanics and modeling in mechanobiology · 2023Article
- Location matters: Offset in tissue-engineered vascular graft implantation location affects wall shear stress in porcine models.JTCVS open · 2022Article
- Surgical Planning and Optimization of Patient-Specific Fontan Grafts With Uncertain Post-Operative Boundary Conditions and Anastomosis Displacement.IEEE transactions on bio-medical engineering · 2022Article
- Virtual Reality Cardiac Surgical Planning Software (CorFix) for Designing Patient-Specific Vascular Grafts: Development and Pilot Usability Study.JMIR cardio · 2022Article
- Predicting Hemodynamic Performance of Fontan Operation for Glenn Physiology using Computational Fluid Dynamics: Ten Patient-specific Cases.Journal of clinical images and medical case reports · 2022Article
- Semi-Automatic Planning and Three-Dimensional Electrospinning of Patient-Specific Grafts for Fontan Surgery.IEEE transactions on bio-medical engineering · 2022Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveCustomized Fontan designs, generated by computer-aided design (CAD) and optimized by computational fluid dynamics simulations, can lead to novel, patient-specific Fontan conduits unconstrained by off-the-shelf grafts. The relative contributions of both surgical expertise and CAD to Fontan optimization have not been addressed. In this study, we assessed hemodynamic performance of Fontans designed by both surgeon's unconstrained modeling (SUM) and by CAD.
methodsTen cardiac magnetic resonance imaging datasets were used to create 3-dimensional (3D) models of Fontans. Baseline computational fluid dynamics simulations assessed Fontan indexed power loss (iPL), hepatic flow distribution, and percentage of conduit surface area with abnormally low wall shear stress for venous flow (<1 dyne/cm
resultsEight Fontans were redesigned by SUM and CAD methods. Both SUM and CAD redesigns met iPL thresholds. SUM had lower iPL, whereas CAD demonstrated balanced hepatic flow distribution and lower wall shear stress percentage. Wall shear stress percentage shared an inverse relationship with iPL, preventing oversized Fontan designs.
conclusionsCustomized Fontan conduits with low iPL can be created by either a surgeon or CAD. CAD can also improve hepatic flow distribution and prevent oversized Fontan designs. Future studies should investigate workflows that combine SUM and CAD to optimize Fontan conduits.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.