ArticleeLife2020
Medial entorhinal cortex activates in a traveling wave in the rat.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Dorsoventral gradient of theta sweeps in the medial entorhinal cortex.Science advances · 2026Article
- Traveling waves along the cortical depth reflect structured synaptic inputs.Research square · 2026Article
- Brain-Wide Spatiotemporally Distinct Traveling Waves Drive Anxiety-Like Behaviors in Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Path integration impairments reveal early cognitive changes in subjective cognitive decline.Science advances · 2025Article
- Path integration impairments reveal early cognitive changes in Subjective Cognitive Decline.bioRxiv : the preprint server for biology · 2025Article
- Origin of visual experience-dependent theta oscillations.Current biology : CB · 2025Article
- Horizontal cortical connections shape intrinsic traveling waves into feature-selective motifs that regulate perceptual sensitivity.Cell reports · 2024Article
- The direction of theta and alpha travelling waves modulates human memory processing.Nature human behaviour · 2024Article
- Horizontal cortical connections shape intrinsic traveling waves into feature-selective motifs that regulate perceptual sensitivity.Research square · 2024Article
- How our understanding of memory replay evolves.Journal of neurophysiology · 2023Review
- Precisely timed theta oscillations are selectively required during the encoding phase of memory.Nature neuroscience · 2021Article
- Cross Laminar Traveling Components of Field Potentials due to Volume Conduction of Non-Traveling Neuronal Activity in Macaque Sensory Cortices.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Distance-tuned neurons drive specialized path integration calculations in medial entorhinal cortex.Cell reports · 2021Article
- Spectrum Degradation of Hippocampal LFP During Euthanasia.Frontiers in systems neuroscience · 2021Article
- Functionally distinct high and low theta oscillations in the human hippocampus.Nature communications · 2020Article
- Correlated activity favors synergistic processing in local cortical networks in vitro at synaptically relevant timescales.Network neuroscience (Cambridge, Mass.) · 2020Article
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Authors and funding
3 authors at 1 institution in 1 country.
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Abstract
Traveling waves are hypothesized to support the long-range coordination of anatomically distributed circuits. Whether separate strongly interacting circuits exhibit traveling waves remains unknown. The hippocampus exhibits traveling 'theta' waves and interacts strongly with the medial entorhinal cortex (MEC). To determine whether the MEC also activates in a traveling wave, we performed extracellular recordings of local field potentials (LFP) and multi-unit activity along the MEC. These recordings revealed progressive phase shifts in activity, indicating that the MEC also activates in a traveling wave. Variation in theta waveform along the region, generated by gradients in local physiology, contributed to the observed phase shifts. Removing waveform-related phase shifts left significant residual phase shifts. The residual phase shifts covaried with theta frequency in a manner consistent with those generated by weakly coupled oscillators. These results show that the coordination of anatomically distributed circuits could be enabled by traveling waves but reveal heterogeneity in the mechanisms generating those waves.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.