Evidence map›Paper›PMID 32057290›Full record

ArticleSICOT-J2020

Spondylodiscitis: experience of surgical management of complicated cases after failed antibiotic treatment.

Abdullah Mohammed Kamal, Mohammad M El-Sharkawi, Moataz El-Sabrout, Mohammad Gamal Hassan

2 registry-linked trialsAbstract read
In one paragraph

Article in SICOT-J, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04749082 unknown statusnot on this mapstarted 2021, after this paper: background citation

Long Term Follow up of Patients With Thoracolumbar Spondylodiscitis Treated Surgically by Posterior Approach in Assiut University Hospitals

TypeobservationalSponsorAssiut UniversityRan2021 to 2021Enrolled40ConditionsSpondylodiscitis
NCT05806905 unknown statusnot on this mapstarted 2022, after this paper: background citation

Epidemiology, Clinical Features and Diagnosis of Spondylodiscitis at Assiut University Hospital

TypeobservationalSponsorAssiut UniversityRan2022 to 2024Enrolled50ConditionsSpondylodiscitis
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Abdullah Mohammed KamalDepartment of Orthopaedic and Trauma Surgery, Faculty of Medicine, Assiut University, Assiut 71511, Egypt.ORCID 0000-0002-2212-2661
Mohammad M El-SharkawiDepartment of Orthopaedic and Trauma Surgery, Faculty of Medicine, Assiut University, Assiut 71511, Egypt.ORCID 0000-0001-6177-7145
Moataz El-SabroutDepartment of Orthopaedic and Trauma Surgery, Faculty of Medicine, Assiut University, Assiut 71511, Egypt.
Mohammad Gamal HassanDepartment of Orthopaedic and Trauma Surgery, Faculty of Medicine, Assiut University, Assiut 71511, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe term Spondylodiscitis (SD) involves infection of the vertebra (Spondylitis), infection of the intervertebral disc (Discitis), or both (Spondylodiscitis). SD represents a diagnostic and therapeutic challenge to any spine surgeon. Any delay in its diagnosis or management may cause serious long-term morbidity or even lead to mortality. In this study, we report the experience of our Institution in the management of severe and complicated cases of SD.

methodsOver a period of 1 year, 39 patients with the diagnosis of SD were surgically treated in Assiut University Hospital, Assiut, Egypt. The management processes were tailored according to the clinical condition, radiological and lab studies of each case; and patients were then prospectively followed-up until they were cured (for a minimum of 6 months). The outcomes were analyzed, to be able to give recommendations while aiming to improve the overall outcome of such dangerous health issue.

resultsIn this series, patients were managed surgically by drainage and debridement of the infection site with/without instrumented fusion. Results included: satisfactory fusion was achieved in 97.3% of patients (confidence interval [CI] = 0.6856-1.3421). Neurological Improvement Rate (NIR) was 71.5% (Statistically significant improvement P-value = 0.014) and reoperation rate was 5% (CI = 0.00621-0.18525). Mortality rate was 7.7% (CI = 0.016-0.209). Several aspects were analyzed in each case.

conclusionSurgical management of severe and complicated cases of SD allows for effective debridement and rapid cure of inflammation, earlier patient mobilization and significantly shorter duration of antibiotic usage.

Indexed as

multi-disciplinary approachpseudarthrosisspinal fusionspinal infectionspondylodiscitis

Identifiers

PMID32057290
PMCPMC7020778

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.