Evidence map›Paper›PMID 32057087›Full record

ArticleActa dermato-venereologica2020

Patient Preferences in Adjuvant and Palliative Treatment of Advanced Melanoma: A Discrete Choice Experiment.

Juliane Weilandt, Katharina Diehl, Marthe Lisa Schaarschmidt, Felix Kieker, Bianca Sasama, Melanie Pronk, Jan Ohletz, Andreas Könnecke, Verena Müller, Jochen Utikal and 3 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Acta dermato-venereologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  6. Patient Preferences for Post-Radical Cystectomy Treatment in Muscle-Invasive Bladder Cancer: A Discrete Choice Experiment in Japan.International journal of urology : official journal of the Japanese Urological Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Juliane WeilandtDepartment of Dermatology and Phlebology, Vivantes Klinikum im Friedrichshain, Berlin, Germany.
Katharina Diehl
Marthe Lisa Schaarschmidt
Felix Kieker
Bianca Sasama
Melanie Pronk
Jan Ohletz
Andreas Könnecke
Verena Müller
Jochen Utikal
Uwe Hillen
Wolfgang Harth
Wiebke K Peitsch
Vivantes Klinikum · DEKlinikum im Friedrichshain · DEUniversity Hospital Heidelberg · DECharité - Universitätsmedizin Berlin · DEHeidelberg University · DEUniversity Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment paradigms for advanced melanoma have changed fundamentally over recent years. A discrete choice experiment was performed to explore patient preferences regarding outcome (overall response rate, 2-year survival rate, progression-free survival, time to response, type of adverse events, probability of adverse event-related treatment discontinuation) and process attributes (frequency and route of administration, frequency of consultations) of modern treatments for melanoma. Mean preferences of 150 patients with melanoma stage IIC-IV were highest for overall response rate (relative importance score (RIS) 26.8) and 2-year survival (RIS 21.6), followed by type of adverse events (RIS 11.7) and probability of adverse event-related treatment discontinuation (RIS 9.2). Interest in overall response rate and 2-year survival declined with increasing age, whereas process attributes gained importance. Participants who had experienced treatment with immune checkpoint inhibitors valued overall response rate more highly and worried less about the type of adverse events. In conclusion, patients with advanced melanoma consider efficacy of treatment options most important, followed by safety, but preferences vary with individual and disease-related characteristics.

Indexed as

Palliative CarePatient PreferenceAdultAgedAged, 80 and overAge FactorsBiological ProductsChemotherapy, AdjuvantChoice BehaviorDrug Administration RoutesDrug Administration ScheduleEducational StatusFemaleHerpesvirus 1, HumanHumansImmune Checkpoint InhibitorsBiological ProductsBRAF protein, humanImmune Checkpoint InhibitorsMAP Kinase Kinase KinasesProtein Kinase InhibitorsProto-Oncogene Proteins B-raftalimogene laherparepvecBRAF inhibitorsconjoint analysisimmune checkpoint inhibitorsmelanomapatient preferencestargeted therapy

Identifiers

PMID32057087
PMCPMC9128976
OpenAlexW3005867736

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.