Evidence map›Paper›PMID 32056880›Full record

ArticleJournal of affective disorders2020

Concordance between clinician-rated and patient reported outcome measures of depressive symptoms in treatment resistant depression.

Rachel Hershenberg, William M McDonald, Andrea Crowell, Patricio Riva-Posse, W Edward Craighead, Helen S Mayberg, Boadie W Dunlop

Abstract read
In one paragraph

Article in Journal of affective disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Observational
  6. Article
  7. Review
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  13. Validation of the Malay Self-Report Quick Inventory of Depressive Symptomatology in a Malaysian Sample.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Rachel HershenbergDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive NE 3rd Floor, Atlanta, GA 30329, USA.
William M McDonaldDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive NE 3rd Floor, Atlanta, GA 30329, USA.
Andrea CrowellDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive NE 3rd Floor, Atlanta, GA 30329, USA.
Patricio Riva-PosseDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive NE 3rd Floor, Atlanta, GA 30329, USA.
W Edward CraigheadDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive NE 3rd Floor, Atlanta, GA 30329, USA; Department of Psychology, Emory University, Atlanta, GA, 30329, USA.
Helen S MaybergDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive NE 3rd Floor, Atlanta, GA 30329, USA; Departments of Neurology and Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Boadie W DunlopDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive NE 3rd Floor, Atlanta, GA 30329, USA. Electronic address: bdunlop@emory.edu.

Funding

QAQC Johns Hopkins Institute for Clinical and Translational ResearchUL1TR003098 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2019 to 2023
$57.7M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025008 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$29.0M
X LINKED NYSTAGMUS SYNDROME WITH FEATURES OF ALBINISMM01RR000039 · NCRR · EMORY UNIVERSITY · PI QUYYUMI, ARSHED A · 1985 to 2007
$21.3M
Special Scientific Procedures: Statistical Modeling CoreP50MH077083 · NIMH · EMORY UNIVERSITY · PI KUTNER, MICHAEL HENRY · 2006 to 2010
$9.3M
Predictors of Treatment Response Relapse and Recurrence in Major DepressionR01MH080880 · NIMH · EMORY UNIVERSITY · PI CRAIGHEAD, W. EDWARD · 2008 to 2012
$6.6M
Institute for Clinical and Translational ResearchUL1TR000424 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2012 to 2012
$6.0M
Neural Correlates of Loss Aversion in Major DepressionK23MH086690 · NIMH · EMORY UNIVERSITY · PI DUNLOP, BOADIE W · 2009 to 2011
$521k
NCATS NIH HHS UL1 TR000424NCATS NIH HHS UL1 TR003098NCRR NIH HHS M01 RR000039NCRR NIH HHS UL1 RR025008NIMH NIH HHS K23 MH086690NIMH NIH HHS P50 MH077083NIMH NIH HHS R01 MH080880
6 · The paper itself

Abstract

backgroundCalls to implement measurement-based care (MBC) in psychiatry are increasing. A recent Cochrane meta-analysis concluded that there is insufficient evidence that routine application of patient reported outcomes (PROs) improves treatment outcomes for common psychiatric disorders. There is a particular paucity of this information in patients with treatment resistant depression (TRD).

methodsA TRD sample (n = 302) and a treatment-naïve sample with major depression (n = 344) were assessed for the level of agreement in depression severity between two PROs (the Beck Depression Inventory, BDI, and the Quick Inventory of Depressive Symptomatology Self-report, QIDS-SR) and two Clinician Rated (CRs) measures (Hamilton Depression Rating Scale, HDRS, and the Montgomery-Asberg Depression Rating Scale, MADRS).

resultsCorrelations between CR and PRO total scores in the TRD sample ranged from 0.57 (HDRS-QIDS-SR) to 0.68 (MADRS-BDI), reflecting a moderate-to-strong relationship between assessment tools. Correlations in the treatment naïve sample were non-significantly lower for most comparisons, ranging from 0.51 (HDRS-QIDS-SR) to 0.64 (MADRS-BDI). Few predictors of discordance between CRs and PROs were identified, though chronicity of the current episode in treatment-naïve patients was associated with greater agreement. LIMITATIONS: Inter-rater reliability of the clinician interviews was conducted separately within the two studies so we could not determine the reliability between the two groups of raters used in the studies.

conclusionFindings generally supported acceptably high levels of agreement between patient and clinician ratings of baseline depression severity. More work is needed to determine the extent to which PROs can improve outcomes in MBC for depression and, more specifically, TRD.

Indexed as

DepressionDepressive Disorder, Treatment-ResistantHumansPatient Reported Outcome MeasuresPsychiatric Status Rating ScalesPsychometricsReproducibility of ResultsAntidepressantsAssessmentMajor depressive disorderMeasurement based careSelf-reports

Identifiers

PMID32056880
PMCPMC8672917

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.