Evidence map›Paper›PMID 32056878›Full record

ArticleJournal of affective disorders2020

A tale of two systems: Testing a positive and negative valence systems framework to understand social disconnection across anxiety and depressive disorders.

Charles T Taylor, Sarah L Pearlstein, Murray B Stein

Abstract read
In one paragraph

Article in Journal of affective disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  3. The Role of Social Networks on Depression and Anxiety Among a Sample of Urban American Indian/Alaska Native Emerging Adults.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Charles T TaylorDepartment of Psychiatry, University of California, San Diego, La Jolla, CA 92037, United States. Electronic address: c1taylor@ucsd.edu.
Sarah L PearlsteinDepartment of Psychiatry, University of California, San Diego, La Jolla, CA 92037, United States; Department of Psychology, San Diego State University, San Diego, CA 92120, United States.
Murray B SteinDepartment of Psychiatry, University of California, San Diego, La Jolla, CA 92037, United States.

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
Novel Behavioral Intervention to Target Social Reward Sensitivity and AttachmentR61MH113769 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TAYLOR, CHARLES · 2017 to 2018
$1.5M
Positive Emotional Processing: Exploring Novel Treatment Targets in Social PhobiaR00MH090243 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TAYLOR, CHARLES · 2013 to 2015
$657k
NCATS NIH HHS UL1 TR001442NIMH NIH HHS R00 MH090243NIMH NIH HHS R61 MH113769
6 · The paper itself

Abstract

backgroundSocial disconnection is a common and pernicious feature of anxiety and depressive disorders, yet is insufficiently addressed by our best available treatments. To better understand why people with anxiety and depression feel socially disconnected, we tested a positive and negative valence systems framework informed by research on how normative social connections develop and flourish.

methodIndividuals seeking treatment for anxiety or depression (N = 150) completed measures of perceived social connectedness, positive and negative valence temperament, social goals, affect, symptoms, and life satisfaction.

resultsFeeling less socially connected was associated with diminished life satisfaction, beyond clinical symptom severity. Regression analyses revealed that both diminished positive valence and heightened negative valence temperament, and their corresponding motivational and affective outputs, were significantly and uniquely (with no significant interaction between them) associated with lower perceived connectedness. LIMITATIONS: Data was cross-sectional and based on self-report-limiting conclusions about causality and social disconnection processes at different units of analysis.

conclusionsUnderstanding social disconnection through the lens of a positive and negative valence systems framework may inform transdiagnostic models and treatment approaches.

Indexed as

Anxiety DisordersDepressive DisorderAnxietyCross-Sectional StudiesDepressionEmotionsHumansAnxietyDepressionLife satisfactionNegative valencePositive valenceSocial connectedness

Identifiers

PMID32056878
PMCPMC7351468

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.