Evidence map›Paper›PMID 32056766›Full record

Trial reportJournal of affective disorders2020

Visually mediated functioning improves following treatment of hoarding disorder.

Jessica J Zakrzewski, Drew A Gillett, Ofilio R Vigil, Lauren C Smith, Kiya Komaiko, Chia-Ying Chou, Soo Y Uhm, L David Bain, Sandra J Stark, Michael Gause and 8 more

Open access · hybridAbstract readRandomized Controlled TrialEquivalence Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of affective disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Jessica J ZakrzewskiDepartment of Psychiatry, Center for OCD, Anxiety, and Related Disorders, College of Medicine, University of Florida, 100 S Newell Drive, L4-100, Gainesville FL 32610, USA.
Drew A GillettDepartment of Psychiatry, Center for OCD, Anxiety, and Related Disorders, College of Medicine, University of Florida, 100 S Newell Drive, L4-100, Gainesville FL 32610, USA.
Ofilio R VigilDepartment of Psychiatry, University of California, San Francisco and San Francisco VA Medical Center, 401 Parnassus Avenue, San Francisco, CA 94143-0984, USA.
Lauren C SmithDepartment of Psychiatry, University of California, San Francisco and San Francisco VA Medical Center, 401 Parnassus Avenue, San Francisco, CA 94143-0984, USA.
Kiya KomaikoDepartment of Psychiatry, University of California, San Francisco and San Francisco VA Medical Center, 401 Parnassus Avenue, San Francisco, CA 94143-0984, USA.
Chia-Ying ChouDepartment of Psychiatry, University of California, San Francisco and San Francisco VA Medical Center, 401 Parnassus Avenue, San Francisco, CA 94143-0984, USA.
Soo Y UhmDepartment of Psychiatry, University of California, San Francisco and San Francisco VA Medical Center, 401 Parnassus Avenue, San Francisco, CA 94143-0984, USA.
L David BainMental Health Association of San Francisco, San Francisco, CA, USA.
Sandra J StarkMental Health Association of San Francisco, San Francisco, CA, USA.
Michael GauseSonoma County Community Development Commission, USA.
Gillian HowellMental Health Association of San Francisco, San Francisco, CA, USA.
Eduardo VegaMental Health Association of San Francisco, San Francisco, CA, USA.
Joanne ChanMental Health Association of San Francisco, San Francisco, CA, USA.
Monika B EckfieldDepartment of Nursing, California State University, East Bay, CA, USA.
Janice Y TsohDepartment of Psychiatry, University of California, San Francisco and San Francisco VA Medical Center, 401 Parnassus Avenue, San Francisco, CA 94143-0984, USA.
Kevin DelucchiDepartment of Psychiatry, University of California, San Francisco and San Francisco VA Medical Center, 401 Parnassus Avenue, San Francisco, CA 94143-0984, USA.
R Scott MackinDepartment of Psychiatry, University of California, San Francisco and San Francisco VA Medical Center, 401 Parnassus Avenue, San Francisco, CA 94143-0984, USA. Electronic address: Scott.mackin@ucsf.edu.
Carol A MathewsDepartment of Psychiatry, Center for OCD, Anxiety, and Related Disorders, College of Medicine, University of Florida, 100 S Newell Drive, L4-100, Gainesville FL 32610, USA. Electronic address: carolmathews@ufl.edu.
Nia Association · USSan Francisco VA Medical Center · USUniversity of California, San Francisco · USUniversity of Florida · USCalifornia State University, East Bay · US

Funding

MyAPS: Development and Validation of an AI Platform for Generating Emotional PicturesR01MH112558 · NIMH · UNIVERSITY OF FLORIDA · PI MINGZHOU DING, Ruogu Fang · 2017 to 2026
$2.5M
Identifying Intermediate Phenotypes for Compulsive HoardingR21MH087748 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATHEWS, CAROL A · 2010 to 2011
$435k
NIMH NIH HHS R01 MH112558NIMH NIH HHS R21 MH087748
6 · The paper itself

Abstract

backgroundHoarding disorder (HD) is a highly debilitating psychiatric disorder that affects 2-6% of adults. Neuropsychological deficits in visual memory, detection, and categorization have been reported in HD. To date, no study has examined the relationship between neurocognitive functioning and treatment for HD. We aim to determine the association between neurocognitive functioning and treatment outcomes, as well as the impact of HD-specific treatment on cognitive functioning.

methods323 individuals with HD were randomized to 20 weeks of peer- or clinician-led group behavioral treatment. 242 participants completed pre- and post-treatment neuropsychological testing covering eight neurocognitive domains. Rates of cognitive impairment (CI) were assessed for each neurocognitive domain. The association of baseline neurocognitive function on treatment response was examined using multiple regression. MANOVA and post-hoc tests were used to determine neurocognitive performance change pre- to post treatment.

resultsSixty-seven percent of participants had CI on ≥1 cognitive domain. There was no significant effect of pre-treatment neurocognitive functioning on treatment outcome. Post-treatment improvements were observed in visual memory, visual detection, decision making, information processing speed, visuospatial processing, attention/working memory (p≤.001). Declines in performance were found in visual reaction time and categorization. LIMITATIONS: This was a non-inferiority trial to examine two treatment types with no normative comparison group. Treatment seeking individuals are more likely to be insightful, motivated, and have other features which limit generalizability.

conclusionsPatterns of cognitive impairment in HD are similar to previous reports. Pre-treatment neurocognitive functioning did not impact treatment response. Neuropsychological functioning improved across multiple domains following targeted treatment.

Indexed as

Hoarding DisorderAdultAttentionCognitionHumansMemoryNeuropsychological TestsCognitive behavioral therapyCognitive impairmentHoarding disorderNeurocognitive functioningTreatmentVisual functioning

Identifiers

PMID32056766
PMCPMC8056607
OpenAlexW2996159798

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.