Evidence map›Paper›PMID 32056430›Full record

ArticleThe Journal of organic chemistry2020

Synthesis and Biological Evaluation of 4'-Substituted Kaempfer-3-ols.

Sugyeom Kim, Yu Li, Lin Lin, Peyton R Sayasith, Ariel T Tarr, Eric B Wright, Sharia Yasmin, Deborah A Lannigan, George A O'Doherty

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of organic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Triterpenoid Saponins and Flavonoid Glycosides from the Flower ofInternational journal of molecular sciences · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sugyeom KimDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.
Yu LiDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.
Lin LinDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.
Peyton R SayasithDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.
Ariel T TarrDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.
Eric B Wright
Sharia Yasmin
Deborah A Lannigan
George A O'DohertyDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.ORCID 0000-0002-1699-2249
Northeastern University · USVanderbilt University Medical Center · US

Funding

RSK2 in Estrogen Receptor Positive (ER+) Breast CancerR01CA213201 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI LANNIGAN, DEBORAH, SULIKOWSKI, GARY ALLEN · 2018 to 2022
$1.8M
Apramycin scaffold exploration using novel glycochemistry and SAR studies to enhance activity against Acinetobacter baumannii and other multidrug-resistant Gram-negative pathogensR21AI142040 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KIRBY, JAMES E, O'DOHERTY, GEORGE A · 2019 to 2020
$476k
Fusidic acid derivatization to enhance entry into Gram-negative pathogensR21AI146485 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KIRBY, JAMES E, O'DOHERTY, GEORGE A · 2019 to 2020
$475k
Targeted modification of the apramycin 2-deoxystreptamine ring to block aminoglycoside modifying enzyme-based inactivation and enhance potency against multidrug-resistant Gram-negative pathogensR03AI144196 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KIRBY, JAMES E, O'DOHERTY, GEORGE A · 2019 to 2020
$183k
NCI NIH HHS R01 CA213201NIAID NIH HHS R03 AI144196NIAID NIH HHS R21 AI142040NIAID NIH HHS R21 AI146485
6 · The paper itself

Abstract

The synthesis of two series of five kaempfer-3-ols was described. The first set all have a

Indexed as

PhosphorylationCell Proliferation

Identifiers

PMID32056430
PMCPMC7285650
OpenAlexW3005574671

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.