Evidence map›Paper›PMID 32056249›Full record

ReviewJournal of medical virology2020

Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoV.

Jia Liu, Xin Zheng, Qiaoxia Tong, Wei Li, Baoju Wang, Kathrin Sutter, Mirko Trilling, Mengji Lu, Ulf Dittmer, Dongliang Yang

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 315 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
315citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04441502 unknown statusnot on this map

Identification of Predictors for the Evolution of COVID-19 Related Interstitial Pneumonia by Transcriptomic and Seroproteomic Techniques

TypeobservationalSponsorIRCCS Policlinico S. DonatoRan2020 to 2024Enrolled204ConditionsCovid19, Interstitial Pneumonia
NCT04443673 naterminatednot on this map

Controlled and Randomized Clinical Trial for Evaluating the Effect of a Supplement of Glycine as Adjuvant in the Treatment of COVID-19 Pneumonia in Patients Initiating Mechanical Ventilation

TypeinterventionalSponsorInstituto Nacional de Enfermedades RespiratoriasRan2020 to 2021Enrolled59ConditionsCOVID-19, SARS-CoV Infection, SARS (Severe Acute Respiratory Syndrome), SARS PneumoniaArmsGlycine
3 · Its place in the literature

Who cites it

315 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. [Pulmonary innate immune response in Sars-cov-2 infection]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2022
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  5. Renal Injury by SARS-CoV-2 Infection: A Systematic Review.Kidney diseases (Basel, Switzerland) · 2021
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255 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jia LiuDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.ORCID 0000-0002-8262-4997
Xin ZhengDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Qiaoxia TongDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Wei LiDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Baoju WangDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Kathrin SutterInstitute for Virology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany.
Mirko TrillingInstitute for Virology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany.
Mengji LuInstitute for Virology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany.
Ulf DittmerInstitute for Virology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany.
Dongliang YangDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Funding

National Natural Science Foundation of China 81861138044National Natural Science Foundation of China 91642118National Natural Science Foundation of China 91742114National Scientific and Technological Major Project of China 2017ZX10202203
6 · The paper itself

Abstract

First reported from Wuhan, The People's Republic of China, on 31 December 2019, the ongoing outbreak of a novel coronavirus (2019-nCoV) causes great global concerns. Based on the advice of the International Health Regulations Emergency Committee and the fact that to date 24 other countries also reported cases, the WHO Director-General declared that the outbreak of 2019-nCoV constitutes a Public Health Emergency of International Concern on 30 January 2020. Together with the other two highly pathogenic coronaviruses, the severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), 2019-nCov and other yet to be identified coronaviruses pose a global threat to public health. In this mini-review, we provide a brief introduction to the pathology and pathogenesis of SARS-CoV and MERS-CoV and extrapolate this knowledge to the newly identified 2019-nCoV.

Indexed as

BetacoronavirusChinaCommunicable Diseases, EmergingCoronavirus InfectionsCOVID-19Disease OutbreaksHumansMiddle East Respiratory Syndrome CoronavirusPneumonia, ViralSARS-CoV-2Severe Acute Respiratory SyndromeSevere acute respiratory syndrome-related coronaviruscoronavirusimmnopathologyimmune responsespathogenesisrespiratory tractvirus classification

Identifiers

PMID32056249
PMCPMC7166760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.