Evidence map›Paper›PMID 32055977›Full record

ArticleBioprocess and biosystems engineering2020

Co-cultures with integrated in situ product removal for lactate-based propionic acid production.

Ludwig Selder, Wael Sabra, Nikolai Jürgensen, Alagappan Lakshmanan, An-Ping Zeng

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioprocess and biosystems engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Autotrophic lactate production from HApplied microbiology and biotechnology · 2022
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ludwig SelderInstitute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, 21073, Hamburg, Germany.ORCID http://orcid.org/0000-0002-3984-6826
Wael SabraInstitute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, 21073, Hamburg, Germany.
Nikolai JürgensenInstitute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, 21073, Hamburg, Germany.
Alagappan LakshmananInstitute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, 21073, Hamburg, Germany.
An-Ping ZengInstitute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, 21073, Hamburg, Germany. aze@tuhh.de.
Universität Hamburg · DE

Funding

Bundesministerium für Bildung und Forschung 031B0270Bundesministerium für Bildung und Forschung 031B0660E
6 · The paper itself

Abstract

Propionic acid (PA) is a valuable organic acid for the food and feed industry, but no bioproduction at industrial scale exists so far. As product inhibition is a major burden for bioprocesses producing organic acids, in situ product removal (ISPR) is desirable. Here, we demonstrate a new strategy to produce PA with a co-culture coupled with ISPR using electrodialysis. Specifically, Bacillus coagulans first produces lactic acid (LA) from sugar(s) and LA is converted to PA using Veillonella criceti. Applying ISPR to the mentioned co-culture, the specific PA yield was increased from 0.35 to 0.39 g g

Indexed as

BioreactorsBacillus coagulansCoculture TechniquesGlucoseLactic AcidPropionatesVeillonellaXyloseGlucoseLactic AcidPropionatespropionic acidXyloseCo-cultureElectrodialysisIn situ product removalPropionic acid

Identifiers

PMID32055977
PMCPMC7196089
OpenAlexW3006338352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.