Evidence map›Paper›PMID 32055908›Full record

ReviewAnalytical and bioanalytical chemistry2020

Engineering vertically interrogated interferometric sensors for optical label-free biosensing.

Rafael Casquel, Miguel Holgado, María F Laguna, Ana L Hernández, Beatriz Santamaría, Álvaro Lavín, Luca Tramarin, Pedro Herreros

Abstract readReview
In one paragraph

Review in Analytical and bioanalytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Label-Free Optical Resonator-Based Biosensors.Sensors (Basel, Switzerland) · 2020
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rafael CasquelApplied Physics and Materials Engineering Department, Escuela Técnica Superior de Ingenieros Industriales, Universidad Politécnica de Madrid, C/ José Gutierrez Abascal, 2, 28006, Madrid, Spain. rafael.casquel@upm.es.
Miguel HolgadoApplied Physics and Materials Engineering Department, Escuela Técnica Superior de Ingenieros Industriales, Universidad Politécnica de Madrid, C/ José Gutierrez Abascal, 2, 28006, Madrid, Spain. m.holgado@upm.es.
María F LagunaApplied Physics and Materials Engineering Department, Escuela Técnica Superior de Ingenieros Industriales, Universidad Politécnica de Madrid, C/ José Gutierrez Abascal, 2, 28006, Madrid, Spain.
Ana L HernándezOptics, Photonics and Biophotonics Group, Centre for Biomedical Technology, Campus de Montegancedo Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid, Spain.
Beatriz SantamaríaOptics, Photonics and Biophotonics Group, Centre for Biomedical Technology, Campus de Montegancedo Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid, Spain.
Álvaro LavínApplied Physics and Materials Engineering Department, Escuela Técnica Superior de Ingenieros Industriales, Universidad Politécnica de Madrid, C/ José Gutierrez Abascal, 2, 28006, Madrid, Spain.
Luca TramarinOptics, Photonics and Biophotonics Group, Centre for Biomedical Technology, Campus de Montegancedo Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid, Spain.
Pedro HerrerosOptics, Photonics and Biophotonics Group, Centre for Biomedical Technology, Campus de Montegancedo Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid, Spain.

Funding

Spanish RD plan under project HERON TEC2017-84846-R
6 · The paper itself

Abstract

In this work, we review the technology of vertically interrogated optical biosensors from the point of view of engineering. Vertical sensors present several advantages in the fabrication processes and in the light coupling systems, compared with other interferometric sensors. Four different interrelated aspects of the design are identified and described: sensing cell design, optical techniques used in the interrogation, fabrication processes, fluidics, and biofunctionalization of the sensing surface. The designer of a vertical sensor should decide carefully which solution to adopt on each aspect prior to finally integrating all the components in a single platform. Complexity, cost, and reliability of this platform will be determined by the decisions taken on each of the design process. We focus on the research and experience acquired by our group during last years in the field of optical biosensors.

Indexed as

Optical DevicesAnimalsBiosensing TechniquesEquipment DesignHumansInterferometryLightBiosensingInterferometric sensorsNanofabricationOptical sensorsPhotonic calculations

Identifiers

PMID32055908
PMCPMC7214506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.