ArticleIndian dermatology online journal
Comparison of Efficacy of Autologous Platelet-Rich Fibrin versus Unna's Paste Dressing in Chronic Venous Leg Ulcers: A Comparative Study.
Article in Indian dermatology online journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05483777 (Investigation of the Effect of Platelet Rich Fibrin), which is not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of the Effect of Platelet Rich Fibrin (PRF) Application on Wound Healing in Diabetic Foot Wound
Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- The Effectiveness, Safety and Cost-Effectiveness of Platelet-Rich Plasma and Platelet-Rich Fibrin in the Treatment of Venous Leg Ulcers: A Systematic Review and Meta-Analysis.International wound journal · 2026Pooled it
- Clinical efficacy of blood derivatives on wound healing: A systematic review and network meta-analysis.International wound journal · 2024Pooled it
- Impact of autologous platelet concentrates on wound area reduction: A meta-analysis of randomized controlled trials.International wound journal · 2023Pooled it
- Best evidence summary for platelet-rich plasma treatment of chronic wounds.Regenerative therapy · 2026Review
- Effect of platelet-rich fibrin gel combined with alginate dressing on healing of active venous leg ulcers: a randomized clinical trial.Frontiers in medicine · 2026Article
- L-PRF in extra-oral wound care.Periodontology 2000 · 2025Review
- A patient journey mapping study of lived experiences during platelet-rich fibrin gel therapy for venous leg ulcers.Frontiers in medicine · 2025Article
- Platelet-Rich Plasma in Chronic Wound Management: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.Journal of clinical medicine · 2022Review
- Growth Factor Release within Liquid and Solid PRF.Journal of clinical medicine · 2022Article
- Platelet-Rich Fibrin, Preparation and Use in Dermatology.Indian dermatology online journal · 2021Article
- A Comparative Study on Therapeutic Efficacy of Autologous Platelet Rich Fibrin Matrix Versus Zinc Oxide And Phenytoin Paste in Non Healing Ulcers.Indian journal of dermatologyArticle
- The impact of gender and peripheral blood parameters on the characteristics of L-PRF membranes.Journal of oral biology and craniofacial researchArticle
- Comparison of Autologous Platelet-Rich Fibrin Matrix and Transplantation of Autologous Noncultured Epidermal Cell Suspension in the Treatment of Chronic Non Healing Ulcer: Randomized Comparative Study.Indian journal of dermatologyArticle
- Wound Healing by Allogeneic Transplantation of Specific Subpopulation From Human Umbilical Cord Mesenchymal Stem Cells.Cell transplantationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic venous leg ulcers are difficult to treat and recurrences are common. Among various modalities of treatment, platelet-rich fibrin (PRF) has shown promising results in ulcer healing by providing necessary growth factors. Unna's paste dressing has also proven to enhance wound healing.
aimThe aim of this study is to compare the efficacy of autologous PRF versus Unna's paste dressing in chronic venous leg ulcer patients and to compare the mean reduction in ulcer area at the end of 4 weeks. MATERIALS AND
methodsTwenty patients with chronic venous leg ulcers were randomly divided into two groups. Group 1: Patients received PRF dressing which was repeated every week for 4 weeks. Group 2: Patients received Unna's paste dressing once a week for 4 weeks. The ulcer size was assessed with the help of photographs, and ulcer area was measured.
resultsThe mean reduction in the area of the ulcer size in the PRF group was 86.03% and in the Unna's paste group was 71.97%, which was not statistically significant with a
conclusionWe conclude that though there was no statistical significance between the groups, PRF showed a significant reduction in ulcer size.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.