Evidence map›Paper›PMID 32055457›Full record

ArticleBiotechnology reports (Amsterdam, Netherlands)2020

Green synthesis of metallic nanoparticles as effective alternatives to treat antibiotics resistant bacterial infections: A review.

Anirudh Singh, Pavan Kumar Gautam, Arushi Verma, Vishal Singh, Pingali M Shivapriya, Saurabh Shivalkar, Amaresh Kumar Sahoo, Sintu Kumar Samanta

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Biotechnology reports (Amsterdam, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 138 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 1 pooled it
29.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 1 synthesis or guideline pooled it, 584 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Green-synthesized magnetic core-shell NiFeBiochemistry and biophysics reports · 2025
    Article
  18. Article
  19. Article
  20. Article

78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Anirudh SinghDepartment of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, 211012, India.
Pavan Kumar GautamDepartment of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, 211012, India.
Arushi VermaDepartment of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, 211012, India.
Vishal SinghDepartment of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, 211012, India.
Pingali M ShivapriyaDepartment of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, 211012, India.
Saurabh ShivalkarDepartment of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, 211012, India.
Amaresh Kumar SahooDepartment of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, 211012, India.
Sintu Kumar SamantaDepartment of Applied Sciences, Indian Institute of Information Technology Allahabad, Allahabad, 211012, India.
Indian Institute of Information Technology Allahabad · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to development of bacterial resistance to the conventional antibiotics, the treatment of bacterial infections has become a major issue of concern. The unprescribed and uncontrolled use of antibiotics has lead to the rapid development of antibiotic resistance in bacterial strains. Therefore, the development of novel and potent bactericidal agents is of great clinical importance. Interestingly, metallic nanoparticles (NPs) have been proven to be promising alternative to antibiotics. NPs interact with the important cellular organelles and biomolecules like DNA, enzymes, ribosomes, and lysosomes that can affect cell membrane permeability, oxidative stress, gene expression, protein activation, and enzyme activation. Since, NPs target multiple biomolecules concurrently; it becomes very difficult for bacteria to develop resistance against them. Currently, there are different physical and chemical methods utilized for NPs synthesis. However, most of these processes are costly and potentially hazardous for the living organisms and environment. Therefore, there is a need to develop an eco-friendly and cost-effective method of synthesis. Recently, the 'green synthesis' approaches are gaining a lot of attention. It is demonstrated that living organisms like bacteria, yeast, fungi, and plant cells can reduce inorganic metal ions into metal NPs by their cellular metabolites. Both the yield and stability of biogenic NPs are quite satisfactory. In the current article, we have addressed the green synthesis of various metal NPs reported till date and highlighted their different modes and mechanisms of antibacterial properties. It is highly anticipated that biogenic metallic NPs could be viable and economical alternatives for treating drug resistant bacterial infections in near future.

Indexed as

Antibacterial propertyAntibiotics resistanceGreen synthesisMetallic nanoparticles

Identifiers

PMID32055457
PMCPMC7005563
OpenAlexW3003520244

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.