Evidence map›Paper›PMID 32055359›Full record

ArticleChemical science2019

Charge-driven tripod somersault on DNA for ratiometric fluorescence imaging of small molecules in the nucleus.

Kang-Nan Wang, Qian Cao, Liu-Yi Liu, Zi-Jian Zhao, Wenting Liu, Dan-Jie Zhou, Cai-Ping Tan, Wei Xia, Liang-Nian Ji, Zong-Wan Mao

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Article
  3. Light-Driven Cascade Mitochondria-to-Nucleus Photosensitization in Cancer Cell Ablation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kang-Nan WangMOE Key Laboratory of Bioinorganic and Synthetic Chemistry , School of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: caoqian3@mail.sysu.edu.cn ; Email: cesmzw@mail.sysu.edu.cn.ORCID 0000-0002-0835-8803
Qian CaoMOE Key Laboratory of Bioinorganic and Synthetic Chemistry , School of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: caoqian3@mail.sysu.edu.cn ; Email: cesmzw@mail.sysu.edu.cn.
Liu-Yi LiuMOE Key Laboratory of Bioinorganic and Synthetic Chemistry , School of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: caoqian3@mail.sysu.edu.cn ; Email: cesmzw@mail.sysu.edu.cn.
Zi-Jian ZhaoMOE Key Laboratory of Bioinorganic and Synthetic Chemistry , School of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: caoqian3@mail.sysu.edu.cn ; Email: cesmzw@mail.sysu.edu.cn.
Wenting LiuMOE Key Laboratory of Bioinorganic and Synthetic Chemistry , School of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: caoqian3@mail.sysu.edu.cn ; Email: cesmzw@mail.sysu.edu.cn.
Dan-Jie ZhouMOE Key Laboratory of Bioinorganic and Synthetic Chemistry , School of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: caoqian3@mail.sysu.edu.cn ; Email: cesmzw@mail.sysu.edu.cn.
Cai-Ping TanMOE Key Laboratory of Bioinorganic and Synthetic Chemistry , School of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: caoqian3@mail.sysu.edu.cn ; Email: cesmzw@mail.sysu.edu.cn.ORCID 0000-0002-7652-6645
Wei XiaMOE Key Laboratory of Bioinorganic and Synthetic Chemistry , School of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: caoqian3@mail.sysu.edu.cn ; Email: cesmzw@mail.sysu.edu.cn.ORCID 0000-0001-6480-3265
Liang-Nian JiMOE Key Laboratory of Bioinorganic and Synthetic Chemistry , School of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: caoqian3@mail.sysu.edu.cn ; Email: cesmzw@mail.sysu.edu.cn.
Zong-Wan MaoMOE Key Laboratory of Bioinorganic and Synthetic Chemistry , School of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: caoqian3@mail.sysu.edu.cn ; Email: cesmzw@mail.sysu.edu.cn.ORCID 0000-0001-7131-1154
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although fluorescence tracing of small bioactive molecules in living cells has been extensively studied, it is still a challenging task to detect their variations in the nucleus mainly due to the impermeable nuclear membrane and nucleic acid interference. Herein, we take advantage of the nucleic acid enriched environment in the nucleus to establish a strategy, named "charge-driven tripod somersault on DNA", for ratiometric fluorescence imaging of small bioactive molecules in the nucleus. Taking SO

Identifiers

PMID32055359
PMCPMC6991190
OpenAlexW2972276186

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.