Evidence map›Paper›PMID 32055344›Full record

ArticleChemical science2019

Valency engineering of monomeric enzymes for self-assembling biocatalytic hydrogels.

Patrick Bitterwolf, Sabrina Gallus, Theo Peschke, Esther Mittmann, Claude Oelschlaeger, Norbert Willenbacher, Kersten S Rabe, Christof M Niemeyer

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Article
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  7. Review
  8. Article
  9. Surface Display of Complex Enzymes by in Situ SpyCatcher-SpyTag Interaction.Chembiochem : a European journal of chemical biology · 2020
    Article
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Patrick BitterwolfInstitute for Biological Interfaces (IBG1) , Karlsruhe Institute of Technology (KIT) , Hermann-von-Helmholtz-Platz 1 , D-76344 Eggenstein-Leopoldshafen , Germany . Email: niemeyer@kit.edu.
Sabrina GallusInstitute for Biological Interfaces (IBG1) , Karlsruhe Institute of Technology (KIT) , Hermann-von-Helmholtz-Platz 1 , D-76344 Eggenstein-Leopoldshafen , Germany . Email: niemeyer@kit.edu.
Theo PeschkeNovartis AG , Kohlestrasse WSJ 103 , CH-4002 Basel , Switzerland.
Esther MittmannInstitute for Biological Interfaces (IBG1) , Karlsruhe Institute of Technology (KIT) , Hermann-von-Helmholtz-Platz 1 , D-76344 Eggenstein-Leopoldshafen , Germany . Email: niemeyer@kit.edu.
Claude OelschlaegerInstitute for Mechanical Process Engineering and Mechanics , Karlsruhe Institute of Technology (KIT) , Gotthard-Franz-Straße 3 , D-76131 Karlsruhe , Germany.
Norbert WillenbacherInstitute for Mechanical Process Engineering and Mechanics , Karlsruhe Institute of Technology (KIT) , Gotthard-Franz-Straße 3 , D-76131 Karlsruhe , Germany.
Kersten S RabeInstitute for Biological Interfaces (IBG1) , Karlsruhe Institute of Technology (KIT) , Hermann-von-Helmholtz-Platz 1 , D-76344 Eggenstein-Leopoldshafen , Germany . Email: niemeyer@kit.edu.ORCID 0000-0001-7909-8191
Christof M NiemeyerInstitute for Biological Interfaces (IBG1) , Karlsruhe Institute of Technology (KIT) , Hermann-von-Helmholtz-Platz 1 , D-76344 Eggenstein-Leopoldshafen , Germany . Email: niemeyer@kit.edu.ORCID 0000-0002-8837-081X
Karlsruhe Institute of Technology · DENovartis (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All-enzyme hydrogels are efficient reagents for continuous flow biocatalysis. These materials can be obtained by self-assembly of two oligomeric enzymes, modified with the complementary SpyTag and SpyCatcher units. To facilitate access to the large proportion of biocatalytically relevant monomeric enzymes, we demonstrate that the tagging valency of the monomeric (

Identifiers

PMID32055344
PMCPMC6993604
OpenAlexW2971454236

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.