Evidence map›Paper›PMID 32055340›Full record

ArticleChemical science2019

A dual functional ruthenium arene complex induces differentiation and apoptosis of acute promyelocytic leukemia cells.

Hai Huang, Kaiming Cao, Yaqiong Kong, Siming Yuan, Hongke Liu, Yucai Wang, Yangzhong Liu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hai HuangCAS Key Laboratory of Soft Matter Chemistry , Department of Chemistry , University of Science and Technology of China , Hefei , Anhui 230026 , China . Email: liuyz@ustc.edu.cn.ORCID 0000-0003-2123-6533
Kaiming CaoCAS Key Laboratory of Soft Matter Chemistry , Department of Chemistry , University of Science and Technology of China , Hefei , Anhui 230026 , China . Email: liuyz@ustc.edu.cn.
Yaqiong KongJiangsu Key Laboratory of Biofunctional Materials , College of Chemistry and Materials Science , Nanjing Normal University , Nanjing , Jiang Su 210046 , China.
Siming YuanCAS Key Laboratory of Soft Matter Chemistry , Department of Chemistry , University of Science and Technology of China , Hefei , Anhui 230026 , China . Email: liuyz@ustc.edu.cn.
Hongke LiuJiangsu Key Laboratory of Biofunctional Materials , College of Chemistry and Materials Science , Nanjing Normal University , Nanjing , Jiang Su 210046 , China.ORCID 0000-0002-0968-6518
Yucai WangSchool of Life Sciences and Medical Center , University of Science and Technology of China , Hefei , Anhui 230027 , China.ORCID 0000-0001-6046-2934
Yangzhong LiuCAS Key Laboratory of Soft Matter Chemistry , Department of Chemistry , University of Science and Technology of China , Hefei , Anhui 230026 , China . Email: liuyz@ustc.edu.cn.ORCID 0000-0003-2891-7964
University of Science and Technology of China · CNNanjing Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human acute promyelocytic leukemia (APL) is the most malignant form of acute leukemia. The fusion of PML and RARα genes is responsible for over 98% of cases of APL. In this work, we found that a Ru(ii) arene complex, [(η

Identifiers

PMID32055340
PMCPMC6993625
OpenAlexW2970219154

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.