ReviewChemical science2019
Reductive radical-polar crossover: traditional electrophiles in modern radical reactions.
Review in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed.
- Article
- General and efficient access to homoallyl aminesRSC advances · 2026Article
- A radical-polar crossover approach to complex nitrogen heterocycles via the triplet state.Chem · 2026Article
- Photo-enabled and thioamide-directed α-C(spNature communications · 2026Article
- SmIChemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Enzymatic Metal-Hydrogen Atom Transfer with a Cobalt Protoporphyrin Cofactor.Journal of the American Chemical Society · 2026Article
- Photocatalyzed Ring Expansion of α-Ketosulfonylaziridines: Ready Access to δ-Sultams.Angewandte Chemie (International ed. in English) · 2026Article
- Enantioconvergent radical addition of racemic alkyl halides to access vicinal stereocentres.Nature chemistry · 2026Article
- Chloroalkylation of Unactivated Alkenes via a Cobalt-Mediated Radical Ligand Transfer (RLT) Photoredox Catalysis Platform.JACS Au · 2025Article
- Terminal Selective Arylation of Inert Alkanes via Radical-Organometallic Crossover.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Bimolecular Homolytic Substitution (SACS central science · 2025Review
- Unlocking nucleophilic reactivity in Co-MHAT catalysis: Stereospecific backside-backside displacement by anion-activated organocobalt.Science advances · 2025Article
- Organophotoredox Dioxygenation of Alkenes via ROH···F-ActivatedOrganic letters · 2025Article
- Radical-Polar Crossover Bicyclization Enables a Modular Synthesis of Saturated Bicyclic Amines.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Natural Product Synthesis Enabled by Radical-Polar Crossover Reactions.The Journal of organic chemistry · 2025Review
- Modular reductive radical-polar crossover-based acyl migration reactions ofRSC advances · 2025Article
- Photocatalytic Strategy for Decyanative Transformations Enabled by Amine-Ligated Boryl Radical.Organic letters · 2025Article
- Photoredox/Cr-catalyzed enantioselective radical-polar crossover transformation via C-H functionalization.Nature communications · 2025Article
- Recent advances in electrochemical copper catalysis for modern organic synthesis.Beilstein journal of organic chemistry · 2025Review
- Alkene Carboxy-Alkylation via COJournal of the American Chemical Society · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The concept of reductive radical-polar crossover (RRPCO) reactions has recently emerged as a valuable and powerful tool to overcome limitations of both radical and traditional polar chemistry. Especially in case of additions to carbonyl compounds, the synergy of radical and polar pathways is of great advantage since it enables the use of traditional carbonyl electrophiles in radical reactions. The most recent and synthetically important transformations following this line are summarised in the first part of this review. The second part deals with transformations, in which the concept of RRPCO promotes the usage of alkyl halides as electrophiles in radical reactions.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.