ArticleInternational journal of clinical and experimental pathology2020
Discordant lymphoma consisting of mantle cell lymphoma and angioimmunoblastic T cell lymphoma: homology or heterogeneity?
Article in International journal of clinical and experimental pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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6 authors at 1 institution in 1 country.
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Abstract
objectsTo investigate the pathologic characteristic of discordant lymphoma with mantle cell lymphoma and angioimmunoblastic T cell lymphoma.
methodsThe clinicopathologic data of cases of discordant lymphoma were organized and clinicopathologic features were analyzed by literature review.
resultsA 49-year-old male was taken to the hospital due to the lymphandenopathy in January 2007 and mantle cell lymphoma was diagnosed in the pathology report. EBV-EBER staining was negative. Active chemotherapy was received and the patient achieved complete response. Seven years later since diagnosis, in 2014 scattered rashes were found. A skin biopsy was taken and the result was not mantle cell lymphoma but angioimmunoblastic T cell lymphoma. EBV-EBER positivity was detected. Clonal T cell receptor gamma locus gene rearrangements were detected while no clonal immunoglobin heavy locus gene rearrangement was detected in the skin sample.
conclusionsThis is the first report on discordant lymphoma consisting of mantle cell lymphoma and angioimmunoblastic T cell lymphoma. There seems to be no relation these two different kinds of lymphoma, and EBV infection might prompt the development of angioimmunoblastic T cell lymphoma after transplantation. Rash is a common clinical manifestation when T cell lymphoma develops after treatment for MCL.
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32055275PMC7013375W3005770025What OpenQuestion holds
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