ArticleInternational journal of clinical and experimental pathology2020
Superficial CD34-positive fibroblastic tumor: report of two cases and review of literature.
Article in International journal of clinical and experimental pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Cutaneous soft tissue tumors in the 5th edition of the World Health Organization classification of skin tumors: key updates and new entities.Journal of pathology and translational medicine · 2026Article
- Gene fusion-driven cutaneous mesenchymal neoplasms: An updated review emphasizing the emerging entities.Virchows Archiv : an international journal of pathology · 2026Review
- Relative Tumor Density of Soft-Tissue Sarcoma in Korean Population: An Institutional Review.Annals of dermatology · 2025Article
- Diagnostic conundrum of Superficial CD34-positive fibroblastic tumor (SCPFT): a series of five cases.Indian journal of surgical oncology · 2025Article
- Superficial CD34Oncology letters · 2024Article
- Superficial CD34-Positive Fibroblastic Tumor: A Case Series and a Review of Literature.Cureus · 2023Article
- Superficial CD34-Positive Fibroblastic Tumor: Two Case Reports.Annals of dermatology · 2023Article
- Application of modified closed biopsy in rabbit model of VX2-transplanted bone tumor.Journal of orthopaedic surgery and research · 2021Article
- Superficial CD34-positive Fibroblastic Tumour: Unique Subungual Presentation with Confounding Clinical Findings Resembling Fibrokeratoma-like Bowen's Disease.Acta dermato-venereologica · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe studied the clinicopathologic features of superficial CD34-positive fibroblastic tumor (SCPFT), which is a newly described neoplasm, to enhance the recognition and diagnostic level of the disease. CASE PRESENTATION: We herein report two cases of superficial CD34-positive fibroblastic tumors in a 33-year-old man and a 30-year-old man. The 33-year-old man presented with a slow-growing subcutaneous nodule 5.0 cm in diameter on the right thigh, and the 30-year-old man developed a painful lump 4.0 cm in diameter on his right thigh. Histologically, the tumor was located in superficial soft tissue with relative circumscription. Tumors had abundant spindled polygonal cells, which were arranged in fascicular or sheet-like patterns. Neoplastic cells were characterized by polymorphic nuclei, granular cytoplasm, intranuclear cytoplasmic pseudoinclusions, and an extremely low mitotic rate. Immunohistochemically, neoplastic cells showed diffuse and strong CD34 expression and focal cytokeratin staining. The expression of S-100 protein, SMA, CD99, H-caldesmon, ALK-1, and bcl-2 were all negative. The Ki-67 index was low.
conclusionsSCPFT is a rare low-grade fibroblastic tumor that has typical morphologic features and unique biologic behavior. Familiarity with clinicopathologic characteristics of the tumor contributes to the differential diagnosis of similar tumors.
Indexed as
Identifiers
32055270PMC7013377W3013169073What OpenQuestion holds
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