ArticleAnnals of Indian Academy of Neurology
Rationalization of Using the MR Diffusion Imaging in B12 Deficiency.
Article in Annals of Indian Academy of Neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
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- Posterior longitudinal ligament suturation after lumbar discectomy provides postoperative a large intradural area: First report.Journal of craniovertebral junction & spineArticle
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Authors and funding
7 authors.
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Abstract
contextThe structural imaging of brain does not demonstrate any changes in the vast majority of patients with vitamin B12 deficiency, even in the advanced stages.
aimsWe investigated the microstructural changes in the brain with diffusion imaging among patients with biochemical evidence of B12 deficiency. PATIENTS AND
methodsWe retrospectively analyzed all diffusion-weighted MRI images between the periods 2014-2016 who had biochemical evidence of B12. The age-sex matched controls were chosen from the group with normal B12 levels. Patients with pathological findings in conventional MRI images were excluded from the study.
resultsAbout 37 patients were recruited (22 women, 15 men; mean age, 34.1 ± 9.9 years; age range). They were about thirty-four age-and sex-matched controls (with normal B12 levels), which were also included in the study. The mean apparent diffusion coefficient (ADC) value of amygdala (773.8 ± 49.9 vs. 742.2 ± 24.2,
conclusionsOur study indicates that a significant increase in ADC values occurs in multiple brain regions in patients with vitamin B12.
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