ReviewNature reviews. Endocrinology2020
Food as a circadian time cue - evidence from human studies.
Review in Nature reviews. Endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05413486 (Circadian Disturbances in People With Mental Disease), which is not on this map. Cited by 97 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Circadian Disturbances in People With Mental Disease
Who cites it
97 citing papers in PubMed.
- Does Intermittent Nutrition Enterally Normalise hormonal and metabolic responses to feeding in critically ill adults? The DINE-normal proof-of-concept study.Clinical nutrition (Edinburgh, Scotland) · 2025Trial
- Effects of early, late and self-selected time-restricted eating on visceral adipose tissue and cardiometabolic health in participants with overweight or obesity: a randomized controlled trial.Nature medicine · 2025Trial
- Effectiveness of Early Versus Late Time-Restricted Eating Combined with Physical Activity in Overweight or Obese Women.Nutrients · 2025Trial
- Association of meal timing with body composition and cardiometabolic risk factors in young adults.European journal of nutrition · 2023Trial
- Review
- Gut microbiota-mediated modulation of circadian rhythms: Physiological and molecular impacts of dietary composition and feeding time.Journal of food and drug analysis · 2026Review
- Associations of Meal Timing and Temporal Eating Patterns with Cardiovascular Disease Among Chinese Older Adults.Nutrients · 2026Article
- The critical role of gut-brain signalling in eating behaviour and obesity.Nature reviews. Gastroenterology & hepatology · 2026Review
- Meal timing and eating window with all-cause and cardiovascular mortality and life expectancy: population-based cohort study.European journal of clinical nutrition · 2026Article
- Review
- Circadian rhythm: The hidden "puppet master" behind musculoskeletal disorders.Journal of orthopaedic translation · 2026Review
- Associations between chrono-nutrition and glucose metabolism across levels of glucose impairment: The Maastricht Study.European journal of nutrition · 2026Article
- Reward Sensitivity's Associations with Morningness-Eveningness and Other Circadian-Coupled Behavioral Phenomena: A Systematic Review and Meta-Analysis of Cross-Sectional and Prospective Relationships.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2026Article
- Is it time to think about chronotherapy in migraine.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Review
- Identification of biological rhythm disorder profiles and associated problematic digital behaviors among university students: a latent profile analysis.BMC psychology · 2026Article
- Article
- Triage for night eating syndrome (NES) in pregnant women: a cross-sectional pilot study.Hormones (Athens, Greece) · 2026Article
- Cave evolution on repeat: reuse of the same genomic regions across lineages but not across traits inbioRxiv : the preprint server for biology · 2026Article
- Multiomics insights into eating time patterns and cardiovascular risk among Chinese children.Nature communications · 2026Article
- LAMAS (Light, Activity, Meals, & Sleep) timings & burnout, anxiety, and depression in teachers: Protocol for a cross-sectional study.PloS one · 2026Article
37 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Meal timing and composition are frequently reported in the literature as zeitgebers (that is, time cues) for the circadian system of humans and animal models, albeit secondary to light. Although widely assumed to be true, evidence for food zeitgeber effects specific to humans is notably scarce. Fostering zeitgeber hygiene in the general population as the development and practice of healthy use of zeitgebers could potentially reduce chronobiological strain, which is defined as disruption or misalignment within the circadian system. Such chronobiological strain is associated with modern 24/7 lifestyles (for example, shift work) and several negative health outcomes. Adjustments to meal timing and composition are an attractive strategy to synchronize circadian rhythms and develop zeitgeber hygiene. Thus, clarifying the actual effect of meal timing and composition on the human circadian system is a crucial piece of the human chronobiology puzzle. This Review weighs the evidence from human studies pertaining to the hypothesis that food is a circadian zeitgeber by comparing findings against formal zeitgeber criteria put forward by Jürgen Aschoff in the 1950s.
Indexed as
Identifiers
32055029What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.