Evidence map›Paper›PMID 32055021›Full record

SynthesisEye (London, England)2020

Global and regional prevalence of age-related cataract: a comprehensive systematic review and meta-analysis.

Hassan Hashemi, Reza Pakzad, Abbasali Yekta, Mohamadreza Aghamirsalim, Mojgan Pakbin, Shahroukh Ramin, Mehdi Khabazkhoob

Registry-linked trialOpen access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Eye (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05744141 (The Effect Of Relaxation Exercises Before Cataract Surgery On The Anxiety Level Of Elderly İndividuals), which is not on this map. Cited by 190 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
190citing papers in PubMed, 17 pooled it
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05744141 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effect Of Relaxation Exercises Before Cataract Surgery On The Anxiety Level Of Elderly İndividuals

TypeinterventionalSponsorIstanbul University - CerrahpasaRan2022 to 2023Enrolled150ConditionsAnxiety LevelArmsRelaxation Exercises
3 · Its place in the literature

Who cites it

190 citing papers in PubMed, 17 syntheses or guidelines pooled it, 364 citations in OpenAlex.

  1. Pooled it
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  4. Optimizing pain management and pupil dilation in cataract surgery: a systematic review and meta-analysis of phenylephrine/ketorolac (OMIDRIA®).Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Pooled it
  5. A comprehensive investigation of identifying miRNA biomarkers and their potential role in age-related cataract by meta-analysis and bioinformatics analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
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  12. Levels of Trace Elements in the Lens, Aqueous Humour, and Plasma of Cataractous Patients-A Narrative Review.International journal of environmental research and public health · 2022
    Pooled it
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  18. Trial
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130 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Hassan HashemiNoor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran.
Reza PakzadDepartment of Epidemiology, Faculty of Health, Ilam University of Medical Sciences, Ilam, Iran.
Abbasali YektaRefractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohamadreza AghamirsalimEye Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mojgan PakbinNoor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran.
Shahroukh RaminDepartment of Optometry, Faculty of Rehabilitation Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mehdi KhabazkhoobDepartment of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. khabazkhoob@yahoo.com.ORCID http://orcid.org/0000-0003-0801-8793
Noor Eye Hospital · IRShahid Beheshti University of Medical Sciences · IRMashhad University of Medical Sciences · IRMedical University of Ilam · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of our study was to estimate regional and global cataract prevalence, its prevalence in different age groups, and the determinants of heterogeneity and its prevalence. For that, we used international databases such as PubMed, Web of Science, Scopus, Embase, and other sources of information to conduct a systematic search for all articles concerning the prevalence of age-related cataract and its types in different age groups. Of the 9922 identified articles, 45 studies with a sample size of 161,947 were included in the analysis, and most of them were from the Office for the Western Pacific Region (19 studies). Age- standardized pooled prevalence estimate (ASPPE) and 95% confidence interval (95% CI) of any cataract, cortical cataract, nuclear cataract, and posterior subcapsular (PSC) cataract were 17.20% (13.39-21.01), 8.05% (4.79-11.31), 8.22% (4.93-11.52), and 2.24% (1.41-3.07), respectively. Significant effects on heterogeneity were observed for the WHO region in the prevalence of any cataract (b: 6.30; p: 0.005) and study year in the prevalence of nuclear cataract (b: -0.66, p: 0.042). In general, the prevalence of cataract not only varies by region but also by age group, and most cases are over the age of 60 years. We examined the sources of variance in the prevalence of cataract and its different types, and identified age as a responsible factor in the prevalence of any cataract, cortical cataract, nuclear cataract, and PSC of cataract, WHO region in the prevalence of any cataract, and study year in the prevalence of nuclear cataract.

Indexed as

CataractDatabases, FactualHumansMiddle AgedPrevalence

Identifiers

PMID32055021
PMCPMC7376226
OpenAlexW3006371205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.