ArticleEuropean journal of clinical nutrition2020
Longitudinal body composition assessment in healthy term-born infants until 2 years of age using ADP and DXA with vacuum cushion.
Article in European journal of clinical nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- An assessment of methods for measuring body composition in full-term infants: A systematic review.Pediatric research · 2026Pooled it
- Comparison of air displacement plethysmography, dual-energy X-ray absorptiometry, and bioimpedance in 6-week-old and 6-month-old infants.Pediatric research · 2026Article
- Body composition at 2 years of age in moderate and late preterm infants.Journal of pediatric gastroenterology and nutrition · 2026Article
- The proportion of weight gain due to change in fat mass in infants with vs without rapid growth.European journal of clinical nutrition · 2025Article
- Adipose development is consistent across hunter-gatherers and diverges from western references.Proceedings. Biological sciences · 2024Article
- Integrated growth assessment in the first 1000 d of life: an interdisciplinary conceptual framework.Public health nutrition · 2023Review
- Body Composition Assessment by Air-Displacement Plethysmography Compared to Dual-Energy X-ray Absorptiometry in Full-Term and Preterm Aged Three to Five Years.Journal of clinical medicine · 2022Article
- Fat mass and fat-free mass track from infancy to childhood: New insights in body composition programming in early life.Obesity (Silver Spring, Md.) · 2021Article
- Anthropometry-based prediction of body composition in early infancy compared to air-displacement plethysmography.Pediatric obesity · 2021Article
- Early weight gain trajectories and body composition in infancy in infants born very preterm.Pediatric obesity · 2021Article
- Longitudinal telomere length and body composition in healthy term-born infants during the first two years of life.PloS one · 2021Article
- Association Between Fat Mass in Early Life and Later Fat Mass Trajectories.JAMA pediatrics · 2020Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAccelerated gain in fat mass (FM) in early life increases the risk for adult diseases. Longitudinal data on infant body composition are crucial for clinical and research use, but very difficult to obtain due to limited measurement tools and unsuccessful measurements between age 6-24 months. We compared FM% by dual-energy X-ray absorptiometry (DXA), with cushion to reduce movement artifacts, with FM% by air-displacement plethysmography (ADP) and evaluated the reliability of this cushion during DXA by comparing FM% with and without cushion. Subsequently, we constructed sex-specific longitudinal body composition charts from 1-24 months.
methodsIn 692 healthy, term-born infants (Sophia Pluto Cohort), FM% was measured by ADP from 1-6 months and DXA with cushion from 6-24 months. At 6 months, FM% was measured in triplicate by ADP and DXA with and without cushion(n = 278), later on in smaller numbers.
resultsAt 6 months, mean FM% by DXA with cushion was 24.1 and by ADP 25.0, mean difference of 0.9% (Bland-Altman p = 0.321, no proportional bias). Mean FM% by DXA without cushion was 12.5% higher compared to ADP (Bland-Altman p < 0.001). DXA without cushion showed higher mean FM% compared to DXA with cushion (+11.6%, p < 0.001) at 6 months. Longitudinally, FM% increased between 1-6 months and decreased from 6-24 months(both p < 0.001).
conclusionsIn infants, DXA scan with cushion limits movement artifacts and shows reliable FM%, comparable to ADP. This allowed us to construct longitudinal body composition charts until 24 months. Our study shows that FM% increases from 1-6 months and gradually declines until 24 months.
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