Evidence map›Paper›PMID 32054879›Full record

ArticleScientific reports2020

The Dopamine D5 receptor contributes to activation of cholinergic interneurons during L-DOPA induced dyskinesia.

Julia Castello, Marisol Cortés, Lauren Malave, Andreas Kottmann, David R Sibley, Eitan Friedman, Heike Rebholz

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. The Signaling and Pharmacology of the Dopamine D1 Receptor.Frontiers in cellular neuroscience · 2021
    Pooled it
  2. Modulatory effects ofNutrition research and practice · 2026
    Article
  3. Article
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  5. Interaction Between Oxytocin and Dopamine Signaling: Focus on the Striatum.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Julia Castello *Department of Molecular, Cellular & Biomedical Sciences, CUNY School of Medicine, New York, NY, USA.
Marisol Cortés *Department of Molecular, Cellular & Biomedical Sciences, CUNY School of Medicine, New York, NY, USA.
Lauren MalaveDepartment of Molecular, Cellular & Biomedical Sciences, CUNY School of Medicine, New York, NY, USA.
Andreas KottmannDepartment of Molecular, Cellular & Biomedical Sciences, CUNY School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-5435-7502
David R SibleyMolecular Neuropharmacology Section, National Institute of Neurologic Disorders and Stroke, Intramural Research Program, National Institutes of Health, Bethesda, Maryland, USA.
Eitan FriedmanDepartment of Molecular, Cellular & Biomedical Sciences, CUNY School of Medicine, New York, NY, USA.
Heike RebholzDepartment of Molecular, Cellular & Biomedical Sciences, CUNY School of Medicine, New York, NY, USA. heikerebholz@gmail.com.
The Graduate Center, CUNY · USCUNY School of Law · USDanube Private University · ATNational Institutes of Health · US

Funding

Molecular And Pharmacological Studies Of Dopamine ReceptorsZIANS002263 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI SIBLEY, DAVID · 2009 to 2025
$37.4M
Cellular/Molecular Basis of Development: Research CenterG12MD007603 · NIMHD · CITY COLLEGE OF NEW YORK · PI PEZZANO, MARK · 2012 to 2017
$11.5M
RESEARCH SUPPORT FOR BIOMEDICAL CAREERS AT CCNYR25GM056833 · NIGMS · CITY COLLEGE OF NEW YORK · PI STEINBERG, MARK L · 2000 to 2019
$9.9M
NIGMS NIH HHS R25 GM056833NIMHD NIH HHS G12 MD007603
6 · The paper itself

Abstract

The dopamine D5 receptor (D5R) is a Gα

Indexed as

AnimalsCholinergic NeuronsCorpus StriatumDisease Models, AnimalDopamineDyskinesia, Drug-InducedHumansInterneuronsLevodopaMAP Kinase Signaling SystemMiceMice, KnockoutOxidopamineParkinson DiseaseReceptors, Dopamine D5DopamineLevodopaOxidopamineReceptors, Dopamine D5

Identifiers

PMID32054879
PMCPMC7018760
OpenAlexW3006235880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.