Evidence map›Paper›PMID 32054846›Full record

ReviewNature reviews. Disease primers2020

Burn injury.

Marc G Jeschke, Margriet E van Baar, Mashkoor A Choudhry, Kevin K Chung, Nicole S Gibran, Sarvesh Logsetty

5 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Disease primers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 731 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
731citing papers in PubMed, 9 pooled it
86.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04467619 nacompletednot on this map

Influence of Illusory Movements on Metabolism in Patients With Large Burns

TypeinterventionalSponsorCharles University, Czech RepublicRan2020 to 2024Enrolled12ConditionsCatabolic State, Burns, Illusions, KinestheticArmsFunctional Proprioceptive Stimulation
NCT06013553 naunknown statusnot on this mapstarted 2023, after this paper: background citation

The Effect of Aerobic Exercise on Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio and Lymphocyte-Monocyte Ratio in Burn Patients: A Randomized Controlled Study

TypeinterventionalSponsorHasan Kalyoncu UniversityRan2023 to 2023Enrolled30ConditionsBurns, Physiotherapy, Aerobic ExercisesArmsControl Group, Aerobic Exercises group
NCT06160518 nacompletednot on this mapstarted 2023, after this paper: background citation

Technology and Children's Health: Effect of Virtual Reality on Pain and Clinical Outcomes During Hydrotherapy for Children With Burn

TypeinterventionalSponsorMatrouh UniversityRan2023 to 2023Enrolled60ConditionsBurn, HydrotherapyArmsVirtual reality
NCT06899958 nanot yet recruitingnot on this mapstarted 2027, after this paper: background citation

Metabolism Enhancement by Laser Therapy

TypeinterventionalSponsorMassachusetts General HospitalRan2027 to 2029Enrolled15ConditionsMetabolism DisorderArmsFractional Laser
NCT07329595 recruitingnot on this mapstarted 2023, after this paper: background citation

Monitoring the Clinical and Immunological Effects of Microbiome Changes Following Severe Burn Injury

TypeobservationalSponsorTamas Vegh, MDRan2023 to 2026Enrolled30ConditionsSeverely Burned Patients, Gut Microbiota Diversity and Composition, Inflammatory Responses
3 · Its place in the literature

Who cites it

731 citing papers in PubMed, 9 syntheses or guidelines pooled it, 1,458 citations in OpenAlex.

  1. [Practice guideline for adult burn rehabilitation nursing (2026 edition)].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026
    Guideline
  2. Pooled it
  3. Pooled it
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  6. Pooled it
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  8. Guideline
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  10. Trial
  11. Article
  12. CuBioactive materials · 2026
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  14. Review
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  19. A CD14-Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  20. Article

671 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 3 countries.

Marc G JeschkeRoss Tilley Burn Center, Department of Surgery, Sunnybrook Health Science Center, Toronto, Ontario, Canada. marc.jeschke@sunnybrook.ca.
Margriet E van BaarAssociation of Dutch Burn Centres, Maasstad Hospital, Rotterdam, Netherlands.
Mashkoor A ChoudhryBurn and Shock Trauma Research Institute, Alcohol Research Program, Stritch School of Medicine, Loyola University Chicago Health Sciences Division, Maywood, IL, USA.
Kevin K ChungDepartment of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Nicole S GibranDepartment of Surgery, University of Washington School of Medicine, Seattle, WA, USA.
Sarvesh LogsettyDepartments of Surgery and Psychiatry, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Association of Dutch Burn Centres · NLLoyola University Chicago · USSunnybrook Health Science Centre · CAUniformed Services University of the Health Sciences · USUniversity of Manitoba · CAUniversity of Washington · US

Funding

Intestinal bacteria and epithelial barrier disruption after alcohol and burn injuryR01GM128242 · NIGMS · LOYOLA UNIVERSITY CHICAGO · PI CHOUDHRY, MASHKOOR A · 2018 to 2025
$2.5M
Hepatic ER stress contributes to morbidity and mortality after burn injury.R01GM087285 · NIGMS · SUNNYBROOK & WOMEN'S COLL HLTH SCIS CTR · PI BOEHNING, DARREN F, JESCHKE, MARC GERHARD · 2010 to 2018
$1.9M
NIGMS NIH HHS R01 GM087285NIGMS NIH HHS R01 GM128242
6 · The paper itself

Abstract

Burn injuries are under-appreciated injuries that are associated with substantial morbidity and mortality. Burn injuries, particularly severe burns, are accompanied by an immune and inflammatory response, metabolic changes and distributive shock that can be challenging to manage and can lead to multiple organ failure. Of great importance is that the injury affects not only the physical health, but also the mental health and quality of life of the patient. Accordingly, patients with burn injury cannot be considered recovered when the wounds have healed; instead, burn injury leads to long-term profound alterations that must be addressed to optimize quality of life. Burn care providers are, therefore, faced with a plethora of challenges including acute and critical care management, long-term care and rehabilitation. The aim of this Primer is not only to give an overview and update about burn care, but also to raise awareness of the ongoing challenges and stigmata associated with burn injuries.

Indexed as

BurnsHumansMultiple Organ FailureQuality of LifeShock

Identifiers

PMID32054846
PMCPMC7224101
OpenAlexW4211234775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.