Evidence map›Paper›PMID 32054660›Full record

ArticleDevelopment (Cambridge, England)2020

Maternal Larp6 controls oocyte development, chorion formation and elevation.

Hoi Ting A Hau, Oluwaseun Ogundele, Andrew H Hibbert, Clinton A L Monfries, Katherine Exelby, Natalie J Wood, Jessica Nevarez-Mejia, M Alejandra Carbajal, Roland A Fleck, Maria Dermit and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Hoi Ting A HauRandall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK.ORCID 0000-0002-8872-7583
Oluwaseun OgundeleRandall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK.ORCID 0000-0003-1979-6101
Andrew H HibbertRandall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK.
Clinton A L MonfriesRandall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK.ORCID 0000-0003-3604-9677
Katherine ExelbyRandall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK.ORCID 0000-0002-5723-8867
Natalie J WoodRandall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK.ORCID 0000-0002-1150-9035
Jessica Nevarez-MejiaRandall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK.ORCID 0000-0003-3390-4818
M Alejandra CarbajalCentre for Ultrastructural Imaging, King's College London, London SE1 1UL, UK.ORCID 0000-0002-3120-0166
Roland A FleckCentre for Ultrastructural Imaging, King's College London, London SE1 1UL, UK.ORCID 0000-0003-1542-6218
Maria DermitBarts Cancer Institute, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.ORCID 0000-0002-6287-8367
Faraz K MardakhehBarts Cancer Institute, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.ORCID 0000-0003-3896-0827
Victoria C Williams-WardRandall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK.ORCID 0000-0002-7642-9714
Tapan G PipaliaRandall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK.ORCID 0000-0003-3960-1308
Maria R ConteRandall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK.ORCID 0000-0001-8558-2051
Simon M HughesRandall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK simon.hughes@kcl.ac.uk.ORCID 0000-0001-8227-9225
King's College London · GBQueen Mary University of London · GB

Funding

UCI International Research TrainingT37MD001485 · NIMHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI MOTA-BRAVO, LUIS M · 2005 to 2018
$3.5M
Biotechnology and Biological Sciences Research CouncilMedical Research Council G0300213Medical Research Council G1001029Medical Research Council MR/N021231/1Medical Research Council MR/P009417/1NIMHD NIH HHS T37 MD001485Wellcome TrustWellcome Trust 093389/Z/10/Z
6 · The paper itself

Abstract

La-related protein 6 (Larp6) is a conserved RNA-binding protein found across eukaryotes that has been suggested to regulate collagen biogenesis, muscle development, ciliogenesis, and various aspects of cell proliferation and migration. Zebrafish have two Larp6 family genes:

Indexed as

AnimalsAutoantigensCell MovementCell ProliferationChorionCollagenEgg ProteinsFemaleGene EditingGene Expression ProfilingGene Expression Regulation, DevelopmentalGenomeGenotypeHeterozygoteHomozygoteLectinsAutoantigenschorion proteinsCollagenEgg ProteinsLectinsRibonucleoproteinsSS-B AntigenChorionKnockoutLarp6Mass spectrometryMaternal effectOocyteZebrafish

Identifiers

PMID32054660
PMCPMC7055395
OpenAlexW3006238428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.