Evidence map›Paper›PMID 32054527›Full record

ArticleBiological research2020

CtpB is a plasma membrane copper (I) transporting P-type ATPase of Mycobacterium tuberculosis.

Andrés León-Torres, Epifania Arango, Eliana Castillo, Carlos Y Soto

Open access · goldAbstract read
In one paragraph

Article in Biological research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.4field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. A copper uptake ABC transport system is essential forEmerging microbes & infections · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Structural and functional characterization of mycobacterial PhoH2 and identification of potential inhibitor of its enzymatic activity.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  10. Unique underlying principles shaping copper homeostasis networks.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2022
    Review
  11. Article
  12. Article
  13. CtpB FacilitatesInternational journal of molecular sciences · 2022
    Article
  14. Article
  15. A Role forInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrés León-TorresChemistry Department, Faculty of Sciences, Universidad Nacional de Colombia, Carrera 30  N° 45-03, Ciudad Universitaria, Bogotá, Colombia.
Epifania ArangoChemistry Department, Faculty of Sciences, Universidad Nacional de Colombia, Carrera 30  N° 45-03, Ciudad Universitaria, Bogotá, Colombia.
Eliana CastilloChemistry Department, Faculty of Sciences, Universidad Nacional de Colombia, Carrera 30  N° 45-03, Ciudad Universitaria, Bogotá, Colombia.
Carlos Y SotoChemistry Department, Faculty of Sciences, Universidad Nacional de Colombia, Carrera 30  N° 45-03, Ciudad Universitaria, Bogotá, Colombia. cysotoo@unal.edu.co.ORCID http://orcid.org/0000-0001-8694-7489
Universidad Nacional de Colombia · CO

Funding

Colciencias FP44842-108-2016
6 · The paper itself

Abstract

backgroundThe intracellular concentration of heavy-metal cations, such as copper, nickel, and zinc is pivotal for the mycobacterial response to the hostile environment inside macrophages. To date, copper transport mediated by P-type ATPases across the mycobacterial plasma membrane has not been sufficiently explored.

resultsIn this work, the ATPase activity of the putative Mycobacterium tuberculosis P

conclusionsThe overall results suggest that M. tuberculosis CtpB is associated with Cu

Indexed as

Cell MembraneCopper-Transporting ATPasesMycobacterium tuberculosisCopper-Transporting ATPasesCopper transportCtpBMycobacterium tuberculosisPlasma membraneP-type ATPase

Identifiers

PMID32054527
PMCPMC7017476
OpenAlexW3007836247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.