SynthesisBMC neurology2020
Modern treatment of perineuriomas: a case-series and systematic review.
Synthesis in BMC neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Characterizing Pain in Peripheral Nerve Tumors: Interim Results from a Prospective Bicenter Cohort.Cancers · 2026Article
- Article
- The PERISCOPE Cohort: A Retrospective Study of Clinicopathological and TRAF7 Genetic Findings in Intraneural Perineurioma.European journal of neurology · 2026Article
- Beyond nerve tumors: Differential diagnoses in suspected peripheral nerve sheath tumors.Brain & spine · 2026Article
- Periclavicular multifocal, infiltrative extraneural soft tissue perineuriomas: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Utility of ultrasound in the diagnosis and management of a radial nerve perineurioma in a pediatric patient.Surgical neurology international · 2025Article
- Article
- A 22-year-old man with a posterior left shoulder mass.Skeletal radiology · 2024Article
- Article
- Article
- Benign peripheral nerve sheath tumors: an interdisciplinary diagnostic and therapeutic challenge.Neurosurgical review · 2023Article
- Unusual Clinical Presentation of a Benign Peripheral Nerve Sheath Tumor of the Radial Nerve.Eplasty · 2023Article
- Rare Tumors Causing Median Nerve Compression in Adults-A Narrative Review.Archives of plastic surgery · 2022Article
- Article
- Acral perineurioma: A case report of a rare neoplasm successfully treated with autologous skin graft reconstructive surgery.Dermatology reports · 2022Article
- [Intraneural perineurioma of the radial nerve in the spiral canal as the cause of a 6-year progressive paresis of hand and finger extension].Der Nervenarzt · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPerineuriomas are rare benign peripheral nerve sheath tumours of perineurial cell origin and can be classified into intraneural and extraneural perineuriomas. They most commonly present a mononeuropathy of gradual onset and slow progression, resulting in progressive neurological deficits like hypoesthesia or motor weakness. Therapy is still variable. Aim of the study was to compare our surgical treatment and our follow-up regime including high-resolution nerve sonography with the current literature to evaluate best treatment of perineuriomas.
methodsRetrospective analysis of our dataset "peripheral nerve lesion" to identify patients suffering from perineuriomas between 01.01.2012 until 31.12.2018. Surgical treatment and the follow-up examination of three patients were described. Additionally, a systematic review including PubMed, the Cochrane Collaboration Library, Scopus and Google Scholar was performed for literature published between January 1, 1990 and October 31, 2019 independently by 2 authors.
resultsIn the first case, the left ulnar nerve was affected. In the second case, the left peroneal nerve and in the third case the right median nerve was affected. High-resolution nerve sonography was performed in each case. All patients underwent interfascicular neurolysis combined with a targeted fascicular biopsy under electrophysiological monitoring. Neurological deficits improved subsidized by rehabilitation. Surgical therapy and the neurological outcome were compared with literature. Systematic review revealed 22 articles, which met the inclusion criteria. Therefore, demographics, surgical treatment and neurological outcome of 77 patients were analysed.
conclusionsPerineuriomas are rare benign nerve sheath tumours with a slow progression, sometimes difficult to diagnose. Decompression and neurolysis may improve neurological deficits. High resolution nerve sonography might serve as a helpful additional diagnostic tool in this process.
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